Immobilization of Olive Leaf Extract with Chitosan Nanoparticles as an Adjunct to Enhance Cytotoxicity
Burcu Özdamar,
Yusuf Sürmeli,
Gülşah Şanlı-Mohamed
Abstract:We immobilized the olive leaf extract (OLE) with chitosan
nanoparticles
(CNPs) by optimizing the effect of various immobilization conditions,
and OLE-loaded CNPs (OLE-CNPs) were then elaborately characterized
physicochemically by scanning electron microscopy (SEM), Fourier transform
infrared (FT-IR) spectroscopy, dynamic light scattering (DLS), and
atomic force microscopy (AFM). Under optimal conditions, CNPs were
able to accommodate the OLE with a loading capacity of 97.5%. The
resulting OLE-CNPs had a spheri… Show more
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