Immobility, Hypoxemia, and Pulmonary Arteriovenous Shunting

Ray, Jefferson F.

doi:10.1001/archsurg.1974.01360040055014

Cited by 47 publications

(14 citation statements)

References 21 publications

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“…VAP was microbiologically confirmed in 25% of patients in the no PEEP group and in 9% of patients in the PEEP group. Animal experiments have demonstrated that short body-turning intervals are effective in preventing atelectasis (14). In accordance with previous results (15), the present study confirms that kinetic bed therapy diminishes atelectasis.…”

supporting

confidence: 93%

Prevention of VAP: “WHAP” should we do?*

Schultz

Juffermans

2010

Critical Care Medicine

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supporting

confidence: 93%

Prevention of VAP: “WHAP” should we do?*

Schultz

Juffermans

2010

Critical Care Medicine

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“…In animal studies, 14 immobilization is associated with hypoxemia and atelectasis in the dependent lung. This is alleviated by rotation to alternating lateral positions on a half-hourly basis.…”

Section: Discussionmentioning

confidence: 98%

Evaluation of kinetic therapy in the prevention of complications of prolonged bed rest secondary to stroke.

Kelley

Vibulsresth

Bell

et al. 1987

Stroke

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We performed a prospective, controlled study of kinetic therapy in acute, severe stroke. This therapy involved continuous mobilization of a bedridden patient by means of a specially designed rotating bed. All patients with acute stroke presenting to the Neurology Service over an 18-month period were screened, and those that qualified were assigned to confinement in either a routine hospital bed or a rotating bed. We found that the most common complication of stroke with bed confinement of 4 days or longer was bacterial infection consisting of either pneumonia, sepsis, or urinary tract infection. The two variables found to be of greatest significance in affecting the rate of infection were length of bed confinement, especially for > 13 days (2.3-fold increased risk, p<0.04), and placement in a routine hospital bed (2.9-fold increased risk, p = 0.023). (Stroke 1987;18:638-642)

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“…This is in striking contrast to normal human beings who, even during sleep, change their position approximately every 11.6 min-a phenomenon described by Keane 1 as "minimum physiological mobility requirement." The deleterious effects of prolonged immobilization affect the heart, vascular system, musculoskeletal system, skin, and kidneys, despite repositioning every 2 h. [2][3][4][5][6][7][8] Significant effects may also occur in the respiratory system. Nosocomial pneumonia, pulmonary thromboembolism, and hypoxemia may increase the patient's morbidity and mortality.…”

mentioning

confidence: 99%