“…While adverse consequences from OUD are similar for immigrant and non-immigrant U.S. adults, contextual factors stemming from having marginalized identities and issues related to acculturation bring nuance and susceptibility for comorbid conditions for immigrants in particular (i.e., infectious diseases, psychiatric conditions, polysubstance use) (Bart, 2018;Epelbaum et al, 2010;Guarino et al, 2012;Guarino et al, 2015;Salas-Wright et al, 2018;). Alongside the differences in patterns and acceptability of drug use in the U.S., as compared to immigrant countries of origin, the additional stressors from migration (i.e., family separation, exposure to violence, poverty) may lead to psychiatric comorbid conditions (i.e., depression and anxiety) and/or poly-substance use as selfmedication among immigrants (Kagotho, Maleku, Baaklini, Karandikar, & Mengo, 2020).…”