Immersion immunization of common carp with bacterial ghost‐based DNA vaccine inducing prophylactic protective immunity against spring viraemia of carp virus

Abstract

Aquaculture products represent a key component of world trade (Naylor et al., 2000). According to the State of World Fisheries and Aquaculture 2020 report released by the FAO, the data showed that global aquaculture production reached 82.1 million tons in 2018, accounting for 46% of total aquatic products. Nevertheless, the frequent outbreak of infectious disease in aquatic animal has attracted more and more public attention on the development of aquaculture fishery (Gao et al., 2020). OIE has listed the spring viraemia of carp (SVC) as one of the animal diseases as notifiable (Ashraf et al., 2016). This disease usually breaks out with the spring and causes a large number of deaths in young fish once infected (Kanellos et al., 2006).Researchers have been working to find effective ways to prevent and control spring viraemia of carp virus (SVCV), but there is no approved treatment (Boonthai et al., 2017).

A review on the recent advances and application of vaccines against fish pathogens in aquaculture

“…Another promising bacterial ghost–based DNA vaccine was reported to be effective in common carp against SVCV based on Escherichia coli DH5α. It also improved the immune efficiency of the vaccine on a large scale (Zheng et al 2021 ).…”