Immediate sealing of arterial puncture site following femoropopliteal angioplasty: A prospective randomized trial

Abstract

Compared with manual compression HPCD is faster and more accurate for sealing the arterial puncture defect following angioplasty. After an initial learning curve, it is easy to handle and time-saving as well as convenient for the patient. Furthermore, immediate and full anticoagulation is possible and arterial inflow is not compromised. A drawback is the necessity of an 8 Fr sheath. Nevertheless, the complication rate is comparably low for both methods.

4-French–Compatible Endovascular Material Is Safe and Effective in the Treatment of Femoropopliteal Occlusive Disease: Results of the 4-EVER Trial

“…Furthermore, an increase in compression time leads to higher costs. 25,26 Access site complication rates .10% after interventional procedures can frequently be found in the literature. 27 Vascular closure devices (VCD) were introduced to reduce the time to hemostasis and enhance the safety of percutaneous interventions, as reflected in less bleeding and fewer access site complications.…”

“…Literature review for occurrence of puncture site-related complications during interventional procedures, either by manual compression or with a VCD, reveals comparable rates for hematoma (up to 16%), bleeding (up to 9%), and pseudoaneurysm (up to 8%). [25][26][27][28][29][30][31][32][39][40][41][42][43][44][45][46] Within the 4-EVER study, we evaluated the use of a complete low-profile approach during endovascular intervention. The only access site complications in this study with 4-F systems were hematoma (3.3%) at the puncture site not requiring surgical repair.…”

Comparison of Collagen-Based Vascular Closure Devices in Patients With vs. Without Severe Peripheral Artery Disease

“…The details of Angio-Seal device deployment and its composition has been described previously. 28,29 In brief, the device consists of an absorbable intraluminal component (''anchor'') and a small collagen plug. The anchor is deployed intraluminally such that the arterial wall and the arteriotomy site are ''sandwiched'' between the anchor and the collagen plug, inducing hemostasis.…”

Network Meta-analysis of Randomized Trials on the Safety of Vascular Closure Devices for Femoral Arterial Puncture Site Haemostasis

“…Two trials 12 13 were further excluded due to zero events in both arms. Finally, 40 trials 6 7 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 were included in this meta-analysis. The screening process is shown in Fig.…”