Immediate outcome of neonates with maternal hypertensive disorder of pregnancy at a neonatal intensive care unit

Abstract

Aims : Hypertensive disorders in pregnancy remain a major cause of maternal and neonatal morbidity and mortality worldwide. This study prospectively examined the immediate neonatal outcome of women with maternal hypertensive disorder of pregnancy( HDP).Methods : Sixty mothers and their newborn were selected. Mothers with gestational hypertension, preeclampsia, preeclampsia superimposed on chronic hypertension and chronic hypertension were included.Results : Forty five (75%) mothers were mutipara and 15(25%) were primipara. Mean maternal age was 26.4 years. Mean gestational age was 34+ 4 weeks. 38 were male and 22 were female with Male: Female ratio was 1.72: 1. Thirty six (60%) were from in patient with regular antenatal check up, 60% mothers had gestational hypertension. Fifty four (90%) mothers needed lower uterine caesarian section. Forty four (73.33%) delivered preterm before 36 weeks of pregnancy. Low birth weight (<2.5kg) babies were 30(50%), very low birth weight (<1.5kg) were 16(26.66%). Intrauterine growth retardation (IUGR) were 18(30%) and Appropriate for gestational age( AGA) were 14(23.33%). Respiratory distress 30(50%) were the most common cause of admission, other associated problems were perinatal asphyxia (PNA) with seizure and meconium aspiration syndrome and to rule out sepsis in suspected cases. Nine (15%) needed ventilator care and 6(10%) needed nasal continuous positive airway pressure (NCPAP) for respiratory problem. 6(10%) babies were expired and 54(90%) survived. Average hospital stay were 18.32(±10.68) days with a highest hospital stay of 49 days and the lowest 4 days. Conclusion :Maternal hypertensive disorder of pregnancy is associated with neonatal morbidity.

Risk Factors of Persistent Pulmonary Hypertension of Newborn (PPHN) in Different Gestation

“…We have found a significant risk for PPHN among mothers with asthma in our study. We also got maternal PET as a significant risk factor for developing PPHN in newborns which is consistent with various studies [21][22][23][24]. It has been reported by many authors that RDS and PPHN are associated [17,21].…”

The impact of pregnancy induced hypertension on low birth weight in Ethiopia: systematic review and meta-analysis

“…In Ethiopia, the burden of PIH ranges from 2.23 to 18.25% [ 25 , 26 ]. So, LBW is a complex syndrome that includes preterm neonates, small for gestational age neonates and the overlap between these two situations, typically have the worst outcomes [ 27 ]. In addition, PIH also responsible for nearly one tenth of maternal mortality in middle and low income countries and one-fifth maternal mortality Ethiopia [ 28 ].…”

Jaundice and its associated factors among neonates admitted to selected referral hospitals in southwest oromia, Ethiopia: Multi-center cross-sectional study

“…This finding was in line with studies done in Turkey [ 36 ], India [ 53 ], Iran [ 54 ] and China [ 55 ]. The possible reason is hypertension during pregnancy leads to cause abnormal coagulation profile with bleeding on babies which increase bilirubin level in the blood [ 56 ]. In addition, gestational hypertension might be result in prematurity which fails to conjugate normally produced bilirubin from red blood cell which results in jaundice [ 57 ].…”