Immediate outcome and risk factors determining the outcome of status epilepticus in children attending tertiary care centre

Abstract

Background: Status epilepticus (SE) is a paediatric and neurological medical emergency, continuous seizure lasting more than 30 min, or two or more seizures without full recovery of consciousness between any of them. Determination of immediate outcome of SE in children in a tertiary care hospital and to identify the risk factors influencing the outcome was the objectives of the present study.Methods: A study was conducted in Dept of Pediatrics, Tirunelveli Medical College Hospital among the children from 1 month to12 years of age, who had admitted for SE in hospital’s pediatric causality from October 2009 to October 2010 were selected for the study.Results: Out of 92 patients, total 87 patients completed the study and out of those 74 have recovered and 13 have died. The risk factors significantly affecting the outcome were hypoxia at the time of arrival, decompensated shock, respiratory failure requiring intubation and acidosis.Conclusions: Proper prehospital therapy, early referral, proper care while transporting, anticipitating risk factors involved, and protocol based approach uniformly at all hospital can reduce the mortality due to status epilepticus in children.

The etiologies and outcome of convulsive status epilepticus in children at tertiary care hospital Kashmir India

“…Similar risk factors were found in other studies. 10,[15][16][17] In our study, the outcome was good among cases who had traveled <10 km and was very high among 24 children who had traveled more than 40 km. The study revealed that the lower the distance to the treating hospital, the better the outcome and vice voce.…”

“…The mortality rate in the present study was 14.9% and the mortality rate in children with CSE ranged from 14 to 33% in different other Indian studies, whereas the studies from developed countries report mortality of 9-11%. 9,[15][16][17][18] The risk factors that were significantly associated with mortality in this study, included longer duration of status, acute symptomatic etiology, the requirement of ventilatory support, and circulatory impairment at the time of admission to the hospital. Similar risk factors were found in other studies.…”

Convulsive status epilepticus in children: clinical profile and outcome in a tertiary care hospital

“…Mortality rate in children with CSE ranged from 14-33% in Indian studies while studies from developed countries report mortality of 9-11%. 5,7,8,16,18 The risk factors for mortality that were significant in this study included longer duration of status, acute symptomatic etiology, requirement of ventilatory support and circulatory impairment.…”