Abstract:The patient-specific titanium meshes and immediate particulate autogenous bone graft showed satisfactory clinical and surgical results in improving patients' quality of life and decreasing the overall treatment time with adequate functional rehabilitation.
“…22 Following centrifugation, three different fractions are obtained. 23 1. The test tube's bottom contains concentrated red blood cells, which can be thrown away.…”
Section: Prf Preparationmentioning
confidence: 99%
“…The PRF was gathered 2 mm below the bottom dividing line after the top straw-colored layer had been removed. 23…”
Section: Making and Advanced Prfmentioning
confidence: 99%
“…The suggested centrifugation method (2700 rpm, 12 minutes) was used to create the S-PRF 25 clot, and it resulted in a solid fibrin clot with a tiny interfibrous gap. 23 Using traditional histochemical staining methods, cells could be seen throughout the clot, although they were more elusive in the PRF clot's more distributed regions. 23…”
Numerous studies have been done on the use of biocompatible materials in regenerative medicine. Platelet concentrates, also known as concentrated growth factor, platelet-rich fibrin, and platelet-rich plasma, are the result of centrifuging blood to separate out the platelets. Platelet concentrations have generated a great deal of discussion in both soft and hard tissue engineering. In fact, growth factors, fibrin matrix, and platelets are among the components of autologous platelet concentrate that are essential for the healing of wounds. Modern techniques for tissue restoration by increasing the properties of autologous platelet concentrates are the subject of current research. The usage of platelet concentrates and their role in tissue regeneration are addressed in the current study, along with a number of new advances and its biological effects.
“…22 Following centrifugation, three different fractions are obtained. 23 1. The test tube's bottom contains concentrated red blood cells, which can be thrown away.…”
Section: Prf Preparationmentioning
confidence: 99%
“…The PRF was gathered 2 mm below the bottom dividing line after the top straw-colored layer had been removed. 23…”
Section: Making and Advanced Prfmentioning
confidence: 99%
“…The suggested centrifugation method (2700 rpm, 12 minutes) was used to create the S-PRF 25 clot, and it resulted in a solid fibrin clot with a tiny interfibrous gap. 23 Using traditional histochemical staining methods, cells could be seen throughout the clot, although they were more elusive in the PRF clot's more distributed regions. 23…”
Numerous studies have been done on the use of biocompatible materials in regenerative medicine. Platelet concentrates, also known as concentrated growth factor, platelet-rich fibrin, and platelet-rich plasma, are the result of centrifuging blood to separate out the platelets. Platelet concentrations have generated a great deal of discussion in both soft and hard tissue engineering. In fact, growth factors, fibrin matrix, and platelets are among the components of autologous platelet concentrate that are essential for the healing of wounds. Modern techniques for tissue restoration by increasing the properties of autologous platelet concentrates are the subject of current research. The usage of platelet concentrates and their role in tissue regeneration are addressed in the current study, along with a number of new advances and its biological effects.
“…RP can be utilized at multiple levels of the head and neck reconstruction process. It can be utilized to build either patient-specific implants such as inert titanium plating for maxillary or mandibular reconstruction or for biologic implants such as tissue scaffolding [6][7][8] . RP can also be employed to build tailored cutting guides based on image-guided modeling to improve the osteotomy accuracy in bony contouring.…”
Section: Rapid Prototyping For Head and Neck Reconstructionmentioning
confidence: 99%
“…Similar to VSP, this technique can facilitate pre-operative planning based on idealized anatomy to arrive at three dimensional printed models for use in the operating room. This technique can be organized to become an internal process within an institution with the benefit of reducing costs and preparation time [6][7][8] .…”
Head and neck reconstruction has evolved substantially in the last three decades to rely heavily on microvascular free tissue transfer, including bony composite flaps that improve form and functional outcomes. The technologies available for planning and executing bony reconstruction have undergone concurrent innovation, leaving the modern surgeons with a host of options to consider. In this review, the techniques of external fixation, virtual surgical planning and rapid prototyping are discussed with the aim of familiarizing surgeons and comparing these approaches. External fixation, though not new to head and neck surgery, has seen a revival and has considerable utility in vascularized bony reconstruction with the potential for improved efficiency and cost control. We explore the clinical situations in which virtual surgical planning is best employed, and the varying levels to which it can be applied throughout the reconstructive process. The ever-expanding realm of rapid prototyping, or 3D printing, is also examined to explore potential applications for surgical modeling, tissue engineering and even clinical training. Finally, we present a discussion of the cost-effectiveness of the technologies and future directions for research in the field.
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