Immediate Loading of the Grafted Maxillary Sinus Using Platelet Rich Plasma and Autogenous Bone: A Preliminary Study With Histologic and Histomorphometric Analysis

Abstract

The preliminary results of this clinical study indicate that immediate nonfunctional loading using PRP and 50% autogenous bone combined with different substitute graft materials is a predictable protocol in the grafted maxillary sinus as early as 4 months of postgrafting. The high implant survival rate is due to the early formation of large percentages of new vital bone as confirmed by using histologic and histomorphometric analysis.

Effect of Autologous Growth Factors in Maxillary Sinus Augmentation: A Systematic Review

“…The search provided 28 articles, of which 17 reported on comparative studies investigating the effect of platelet concentrates in maxillary sinus augmentation procedures 20,22–27,29–35,37,38,40 . Three articles were excluded after review of the full text 25,30,33 .…”

“…Three articles were excluded after review of the full text 25,30,33 . The study by Steigmann and Garg 25 was excluded because of inadequate reporting, the Lindeboom and colleagues study 30 was excluded because the only outcome provided was the capillary density of the oral mucosa, while in the study by Lee and colleagues, 33 the platelet concentrate was used in all study groups. Fourteen articles reporting on 12 studies fulfilled all inclusion criteria and were included in the present analysis (Table 1).…”

Immediate Loading of Implants Placed Simultaneously with Sinus Membrane Elevation in the Posterior Atrophic Maxilla: A Two‐Year Follow‐Up Study on 10 Patients

“…In a previous follow-up study on sinus floor augmentation using membrane elevation and simultaneous implant placement by and colleagues, 35 implant primary stability was obtained in 1 to 6 mm of bone below the maxillary sinus. The mean values for single implants were 37.5 Ncm (range: [35][36][37][38][39][40][41][42][43][44][45] and for multiple implants 27.0 Ncm (range: . Such levels of insertion torque and ISQ values have previously been accepted as being high enough to allow for early/immediate loading of the implant.…”

“…[6][7][8][9] An additional bone augmentation procedure may be needed to ensure stability and integration of implants in many cases due to an insufficient amount of bone. 41,42 The aim of the present study was to evaluate immediate loading of implants placed with sinus membrane elevation without additional grafting material for bone augmentation of the maxillary sinus floor. 10,11 Different grafting techniques with the use of different grafting materials have been suggested to increase the amount of bone in order to enable placement of endosseous implants in the posterior maxilla.…”

Porous titanium granules in critical size defects of rabbit tibia with or without membranes

“…6,7,8,9 Deproteinated bovine bone grafts and some ceramic grafts are more stable than autologous bone because of their slow resorption. 10 In addition, these materials represent the most commonly used grafting material for bone regeneration in the orofacial zone.…”