Immediate Breast Reconstruction with SalineFilled Implants: No Interference with the Oncologic Outcome?

Abstract

The possible adverse effects on cancer control due to immediate breast reconstruction have been addressed recently for both silicone-filled implants and flap reconstruction. To evaluate those possible effects after immediate breast reconstruction with saline-filled implants, 49 patients reconstructed with saline-filled breast implants at the Jules Bordet Cancer Institute were studied. Selection was only based on the possibility to find a matched patient. These patients were matched with a control group of 49 matched women with breast cancer treated in the same center by mastectomy without any type of breast reconstruction. The two groups were comparable according to age at diagnosis (within 3 years), year of diagnosis (same year), stage of the tumor, histology, and nodal status. The only difference between the two groups was that radiation therapy was applied to some of the patients who were not reconstructed (due to tumor location). The results show, in terms of local recurrences, distant metastasis, and deaths, no significant difference between the two groups, even for the irradiated patients, within a mean follow-up period of 72 months (range, 24 to 108) months.

Patient satisfaction and health‐related quality of life after autologous tissue breast reconstruction

“…The goal of postmastectomy breast reconstruction is to restore the appearance of the breast and to improve psychological outcomes after cancer ablation. [35][36][37][38] Thus, the assessment of patient outcomes using appropriately constructed and validated instruments is essential to evaluate and quantify the success of these surgeries from the patient's perspective. 39,40 By using specific patient-reported measures, such as the BREAST-Q, the HADS (for measuring general distress), and the IES (for capturing cancer-specific distress), we have analyzed Hr-QOL and satisfaction data in a prospective cohort of 55 patients who underwent free MS-TRAM or DIEP flap breast reconstruction.…”

Patient determinants as independent risk factors for postoperative complications of breast reconstruction

“…In the majority of studies, radiotherapy is shown to adversely affect outcome after implant-based breast reconstructions, with increased late failure rates (5,11,12), poor aesthetic results, loss of symmetry (13)(14)(15), capsular contracture, and infection, even when using the latest generation of implants (5,11,12,14,(16)(17)(18)(19)(20)(21)(22)(23)(24).…”

Immediate reconstruction with implants in women with invasive breast cancer does not affect oncological safety in a matched cohort study

“…Studies addressing the safety of IBR have shown varying rates of local recurrence [17][18][19][20][21][22][23][24][25][26]. As there may be a considerable interval before recurrences occur, confirmation of these results requires a long-term follow-up.…”