Immediate Autogenous Breast Reconstruction in Clinically Advanced Disease

Godfrey, Philip M.; Godfrey, Norman V.; Romita, Mauro C.

doi:10.1097/00006534-199505000-00013

Cited by 57 publications

(26 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At this time, reconstructive surgery should be offered to appropriate patients who are facing mastectomy for breast cancer. 2,6,8,[13][14][15]17,19,[21][22][23]35,38 …”

Section: Discussionmentioning

confidence: 99%

Impact of Immediate Reconstruction on the Local Recurrence of Breast Cancer After Mastectomy

Murphy

Wahhab²,

Rovito³

et al. 2003

Annals of Plastic Surgery

View full text Add to dashboard Cite

The incidence of local recurrence of breast cancer in women who underwent mastectomy with or without reconstruction was examined. All female mastectomy patients were followed-up in a 10-year retrospective review. Groups consisted of patients who had mastectomy, mastectomy with immediate reconstruction, or delayed reconstruction. Reconstruction was performed using prostheses, latissimus dorsi musculocutaneous flaps with or without implants, or transverse rectus abdominis musculocutaneous flaps. Charts were reviewed for local breast cancer recurrence. Statistical analysis was performed using Pearson's chi-square and analysis of variance. Of the 1,444 mastectomies performed from 1988 to 1997, 1,262 breasts (87%) were not reconstructed, 182 (13%) were reconstructed, 158 (87%) were immediately reconstructed, and 24 (13%) were reconstructed later. There were no recurrences in the delayed reconstruction group, two recurrences (1.3%) in the immediate reconstruction group, and nine recurrences (0.7%) in the mastectomy without reconstruction group (p=0.746). Analyses of an additional time period from 1992 to 2000 yielded similar results. There is little relationship between local recurrence of breast cancer after mastectomy and reconstruction.

show abstract

“…At this time, reconstructive surgery should be offered to appropriate patients who are facing mastectomy for breast cancer. 2,6,8,[13][14][15]17,19,[21][22][23]35,38 …”

Section: Discussionmentioning

confidence: 99%

Impact of Immediate Reconstruction on the Local Recurrence of Breast Cancer After Mastectomy

Murphy

Wahhab²,

Rovito³

et al. 2003

Annals of Plastic Surgery

View full text Add to dashboard Cite

show abstract

“…In recent years, skin-sparing mastectomy (SSM) in combination with IBR has gained in acceptance and popularity for early invasive or in situ disease (DCIS) in terms of both oncological safety and acceptable rates of postoperative complications [7][8][9][10][11][12][13][14][15]. More recent reports have also documented the effectiveness of SSM plus IBR for locally advanced disease [16][17][18][19][20][21][22][23][24]. These studies showed complication rates comparable to those of a similar group of patients who did not undergo IBR.…”

Section: Introductionmentioning

confidence: 99%

New concept for immediate breast reconstruction for invasive cancers: feasibility, oncological safety and esthetic outcome of post-neoadjuvant therapy immediate breast reconstruction versus delayed breast reconstruction: a prospective pilot study

Giacalone

Rathat

Daurès

et al. 2010

Breast Cancer Res Treat

View full text Add to dashboard Cite

Feasibility and oncological safety of postadjuvant skin-sparing mastectomy (SSM) plus immediate breast reconstruction (IBR) cannot be evaluated by randomized trials. However, comparative study could modify guidelines for the oncosurgical treatment of invasive breast cancer. Our study compared the feasibility, oncological safety and esthetic outcome of SSM plus latissimus dorsi (LD) flap IBR after chemotherapy (CT) and radiotherapy (RT) with the standard management for invasive breast cancer: mastectomy as primary treatment, adjuvant CT and RT, and LD flap delayed breast reconstruction (DBR). Twenty-six selected patients with stages IIA-IIIA breast cancer were offered post-neoadjuvant SSM plus IBR with LD flap plus implant (IBR group). Seventy-eight other patients had primary mastectomy, adjuvant CT and RT, and LD-assisted DBR (DBR group). After 4.1 years (range 1-8) of follow-up, feasibility, oncological safety, and esthetic outcome were compared. Sixteen (61%) early complications were reported for the IBR group versus 44 (56%) for the DBR group (P = 0.645). Early implant loss was 0% in IBR versus 12% in DBR. IBR had 8 (30%) late complications versus 17 (21%) for DBR (P = 0.362). Capsular contracture and reconstruction failure rates were similar. Local recurrence was 7.7% (2/26) in IBR and 6.4% (5/78) in DBR (P = 0.823). Cosmetic evaluation by independent physicians and by the patients themselves was identical in the two groups. Our concept provides a basis for offering more women the opportunity to elect for immediate reconstruction, even in the setting of radiation therapy.

show abstract

“…For larger tumours (T2 and T3), the problem of radiotherapy after mastectomy does arise. Although some studies have seemed to show that autologous reconstructions tolerate radiotherapy relatively well [13], these results deserve to be confirmed in clinical trials. Skin sparing mastectomy is technically more difficult than modified radical mastectomy since the short incisions make exposure and dissection more difficult.…”

Section: Discussionmentioning

confidence: 95%

Immediate autologous latissimus breast reconstruction after skin sparing mastectomy

Delay

Gratadour

Jorquera

et al. 1999

European Journal of Plastic Surgery

View full text Add to dashboard Cite

A technique of immediate breast reconstruction, combining skin sparing mastectomy and autologous latissimus breast reconstruction, is presented. In this study, 50 patients underwent this procedure between May 1993 and May 1997. The most frequent indication (62%) was ductal carcinoma in situ (multifocal, high grade or larger than 3 cm). In 38% of cases, the patients had a contraindication to the TRAM flap; in the other cases (62%) the patients preferred the dorsal donor site to the abdominal site. Reduction of the contralateral breast was done in 20% of cases of unilateral reconstruction. The aesthetic results, evaluated by two others surgeons, were rated as very good in 88% of cases, good in 8% and poor in 4%. Study of patient satisfaction showed 84% of patients to be pleased, 12% satisfied and 4% poorly satisfied. Dorsal sequelae were rated as slight in 96% of cases, intermediate in 4% and marked in none. The main disadvantage was dorsal seroma which occurred in 62% of cases but was easily managed by repeated aspiration. No patient developed a local recurrence or distant metastases. This technique represents a significant advance in breast reconstruction, giving a breast of natural shape and consistency with no transverse scar or patch effect due to the flap.

show abstract

Immediate Autogenous Breast Reconstruction in Clinically Advanced Disease

Cited by 57 publications

References 0 publications

Impact of Immediate Reconstruction on the Local Recurrence of Breast Cancer After Mastectomy

Impact of Immediate Reconstruction on the Local Recurrence of Breast Cancer After Mastectomy

New concept for immediate breast reconstruction for invasive cancers: feasibility, oncological safety and esthetic outcome of post-neoadjuvant therapy immediate breast reconstruction versus delayed breast reconstruction: a prospective pilot study

Immediate autologous latissimus breast reconstruction after skin sparing mastectomy

Contact Info

Product

Resources

About