“…Most studies included patients with AIS and an active malignancy (AM), defined as patients with a diagnosis of current or metastatic cancer, those undergoing treatment for cancer, or who refused the treatment [ 6 , 7 , 10 , 11 , 13 , 14 , 15 , 16 , 18 , 24 ], and at times patients with a diagnosis made during or after the AIS-hospitalization [ 10 , 14 , 15 ]. This definition was occasionally restricted to a diagnosis within a year or 6months, or cancer treatment within 1–6 months of the ischemic event [ 7 , 11 , 18 , 23 ]. Others utilized ICD codes pertaining to active and metastatic malignancies [ 20 , 21 , 22 ], while certain studies analyzed all patients with any history of cancer [ 9 ], or did not provide a solid definition of active/underlying cancer [ 17 ].…”