Imidazo[4,5-b]Pyridines: From Kinase Inhibitors to more Diversified
Biological Properties

Ferrières, Vincent; Jarmoni, Karim; Misbahi, K.

doi:10.2174/0929867330666230426111650

Cited by 1 publication

(1 citation statement)

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“…This structural affinity facilitates imidazopyridine’s facile interaction with macromolecules such as DNA, RNA, and specific proteins. Moreover, imidazo[4,5- c ]pyridines exhibit notable cytotoxic activity by selectively inhibiting kinase activity [ 29 , 30 , 31 ].…”

Section: Introductionmentioning

confidence: 99%

Imidazopyridine Family: Versatile and Promising Heterocyclic Skeletons for Different Applications

Volpi,

Laurenti,

Rabezzana

2024

Molecules

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In recent years, there has been increasing attention focused on various products belonging to the imidazopyridine family; this class of heterocyclic compounds shows unique chemical structure, versatile optical properties, and diverse biological attributes. The broad family of imidazopyridines encompasses different heterocycles, each with its own specific properties and distinct characteristics, making all of them promising for various application fields. In general, this useful category of aromatic heterocycles holds significant promise across various research domains, spanning from material science to pharmaceuticals. The various cores belonging to the imidazopyridine family exhibit unique properties, such as serving as emitters in imaging, ligands for transition metals, showing reversible electrochemical properties, and demonstrating biological activity. Recently, numerous noteworthy advancements have emerged in different technological fields, including optoelectronic devices, sensors, energy conversion, medical applications, and shining emitters for imaging and microscopy. This review intends to provide a state-of-the-art overview of this framework from 1955 to the present day, unveiling different aspects of various applications. This extensive literature survey may guide chemists and researchers in the quest for novel imidazopyridine compounds with enhanced properties and efficiency in different uses.

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Section: Introductionmentioning

confidence: 99%