Isomeric ligands usually affect the structure and biological activity of complexes. Two Complexes [Zn(tpc)2(H2O)2](1) and [Zn(tfc)2(H2O)2](2) were synthesized with isomerized ligands (Htpc=5-(trifluoromethyl) pyridine-2-carboxylic acid, Htfc=4-(trifluoromethyl) nicotinic acid). Single crystal X-ray...