Imagistic and histopathological description of a cystic nephroma during early second trimester of gestation. Case report.

Abstract

Cystic nephroma is a rare and benign renal tumour of unknown origin, usually diagnosed in the first years of childhood or during adult life. To our knowledge, there are no records in the literature of this particular tumour being descried prenatally. We present a case of a fetus diagnosed with cystic nephroma on 16 weeks of gestation. The renal tumour was evaluated by prenatal ultrasound, post mortem with 7T magnetic resonance imaging, and conventional autopsy.

Clinical and Molecular Characteristics and Outcome of Cystic Partially Differentiated Nephroblastoma and Cystic Nephroma: A Narrative Review of the Literature

“…The surgical approaches included radical nephrectomy in 121 cases and NSS in 28 cases, while the type of surgery was not available for 16 patients. Among the two patients who did not have surgery, one patient had prenatally been diagnosed with CN and polyhydramnios and this patient died before birth due to the premature rupture of membranes at the gestational age of 16 weeks and six days [39]. The other patient had preoperatively been diagnosed with CN through a biopsy, leading to a conservative approach, after which the tumor remained unchanged during a follow-up of eight months [35].…”

“…Six patients died during follow up; in two cases related to CN treatment (post-operative sepsis) [38,45], and in four cases due to complications caused by treating concomitant disease including PPB (n = 2) [46,47] and brain hemorrhage during surgery for cerebral spindle cell sarcoma (n = 1) [48]. In one patient, intrauterine death was reported [39]. We did not identify any relationship between the outcome and chemotherapy treatment in these patients and large series of data that allow statistical analysis are not available.…”