Imaging systems and algorithms to analyze biological samples in real-time using mobile phone microscopy

Shanmugam, A.; Usmani, Mohammad; Mayberry, Addison; Perkins, David L.; Holcomb, Daniel

doi:10.1371/journal.pone.0193797

Cited by 7 publications

(5 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Shanmugam et al used 3D printing to fabricate a custom designed mobile phone microscopy support unit. This unit perfectly aligns the sample compartment with simple optics and a mobile phone camera ( Figure 10 A) [ 116 ]. They also proposed a holder that can incorporate a microfluidic chamber for analyzing flowing samples rather than stationary samples ( Figure 10 B).…”

Section: Applications Of 3d Printing In Diagnosticsmentioning

confidence: 99%

See 1 more Smart Citation

3D-Printed Biosensor Arrays for Medical Diagnostics

2018

View full text Add to dashboard Cite

While the technology is relatively new, low-cost 3D printing has impacted many aspects of human life. 3D printers are being used as manufacturing tools for a wide variety of devices in a spectrum of applications ranging from diagnosis to implants to external prostheses. The ease of use, availability of 3D-design software and low cost has made 3D printing an accessible manufacturing and fabrication tool in many bioanalytical research laboratories. 3D printers can print materials with varying density, optical character, strength and chemical properties that provide the user with a vast array of strategic options. In this review, we focus on applications in biomedical diagnostics and how this revolutionary technique is facilitating the development of low-cost, sensitive, and often geometrically complex tools. 3D printing in the fabrication of microfluidics, supporting equipment, and optical and electronic components of diagnostic devices is presented. Emerging diagnostics systems using 3D bioprinting as a tool to incorporate living cells or biomaterials into 3D printing is also reviewed.

show abstract

Section: Applications Of 3d Printing In Diagnosticsmentioning

confidence: 99%

“…( C ) Support device with sample application hole for paper-based electrochemical detection of butyrylcholinesterase activity. Reproduced with permission from [ 116 ]. Copyright (2018) Elsevier.…”

Section: Figurementioning

confidence: 99%

3D-Printed Biosensor Arrays for Medical Diagnostics

2018

View full text Add to dashboard Cite

show abstract

“…Versatility, ease of design and modification in a fast and economic manner, made 3D printing the method of choice to develop supporting equipment and pieces required for diagnostics. camera [75]. The proposed design composed of a glass slide holder, where samples are spotted for testing.…”

Section: D Printed Supporting Devicesmentioning

confidence: 99%

3D Printed Biosensor Arrays for Medical Diagnostics

Sharafeldin¹,

Jones²,

Rusling³

2018

Preprint

View full text Add to dashboard Cite

While the technology is relatively new, low cost 3D printing has impacted many aspects of human life. 3D printers are being used as manufacturing tools for a wide variety of devices in a spectrum of applications ranging from diagnosis to implants to external prostheses. The ease of use and availability of 3D design software and low cost has made 3D printing an accessible manufacturing and fabrication tool in many research laboratories. 3D printers can print materials with varying density, optical character, strength and chemical properties providing platforms for a huge number of strategies that can be chosen for user's needs. In this review, we focus on applications in biomedical diagnostics and how this revolutionary technique is facilitating development of low cost, sensitive and often geometrically complex tools. 3D printing in fabrication of microfluidics, supporting equipment, optical and electronic components of diagnostic devices is presented. Emerging diagnostic 3D bioprinting as a tool to incorporate living cells or biomaterials into 3D printing is also discussed.

show abstract

“…In previous studies, to compare the accuracy of an optical microscope and a smartphone camera, researchers either used a cradle to fix the smartphone or manufactured and used a special device 20 , 23 , 25 , 26 , 28 , 30 – 32 . These methods were used to obtain consistent smartphone camera images.…”

Section: Introductionmentioning

confidence: 99%

Feasibility of images acquired using smartphone camera for marginal and internal fit of fixed dental prosthesis: comparison and correlation study

Son,

et al. 2024

Sci Rep

View full text Add to dashboard Cite

This study aimed to measure marginal and internal fit using images captured with both an optical microscope and a smartphone camera, comparing the fit measurement performance of these devices and analyzing their correlation. Working casts (with 10 posterior and 10 anterior teeth) created to fabricate fixed dental prostheses were used. These working casts were scanned using a desktop scanner (E1) to design an interim crown, and the designed interim crown was fabricated using a three-dimensional (3D) printer. Utilizing the silicone replica technique, the fabricated interim crown replicated the fit, which was then captured using both an optical microscope and a smartphone camera. The captured images were used to measure the marginal and internal fit according to the imaging device. Intraclass correlation coefficients (ICC) were used for reliability analysis according to the imaging device. Furthermore, the Wilcoxon signed-rank test was adopted for the comparative evaluation of the marginal and internal fit between the imaging devices (α = 0.05). The measurement results of the marginal and internal fit according to the optical microscope and smartphone camera did exhibit a significant difference (P < 0.05). The ICC between the two devices showed an “excellent” agreement of over 0.9 at all measurement points (P < 0.001). A smartphone camera could be used to obtain images for evaluating the marginal and internal fit.

show abstract

Imaging systems and algorithms to analyze biological samples in real-time using mobile phone microscopy

Cited by 7 publications

References 16 publications

3D-Printed Biosensor Arrays for Medical Diagnostics

3D-Printed Biosensor Arrays for Medical Diagnostics

3D Printed Biosensor Arrays for Medical Diagnostics

Feasibility of images acquired using smartphone camera for marginal and internal fit of fixed dental prosthesis: comparison and correlation study

Contact Info

Product

Resources

About