Imaging Social and Environmental Factors as Modulators of Brain Dysfunction: Time to Focus on Developing Non-Western Societies

Crossley, Nicolás; Alliende, Luz María; Ossandón, Tomás; Castañeda, Carmen; González-Valderrama, Alfonso; Undurraga, Juan; Castro, Mariana N.; Guinjoan, Salvador M.; Díaz-Zuluaga, Ana M.; Pineda-Zapata, Julián A; López‐Jaramillo, Carlos; Reyes-Madrigal, Francisco; León-Ortíz, Pablo; Fuente‐Sandoval, Camilo de la; Czepielewski, Letícia Sanguinetti; Gama, Clarissa Severino; Zugman, André; Gadelha, Ary; Jackowski, Andrea Parolin; Bressan, Rodrigo Affonseca

doi:10.1016/j.bpsc.2018.09.005

Cited by 14 publications

(9 citation statements)

References 89 publications

(32 reference statements)

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“…All these programmes were developed alongside research centres or universities, and they had not yet been scaled‐up to the national level. However, more recently, new services have been implemented in the region, new evidence has been produced and a collaborative network for the study of psychosis has been created to move the field forward in the region (N. A. Crossley et al, 2019; N. Crossley et al, 2019). Hence, we aimed to review the state of implementation of EIP services in Latin America.…”

Section: Introductionmentioning

confidence: 99%

Implementation of early psychosis services in Latin America: A scoping review

Aceituno

Mena²,

Vera

et al. 2020

Early Intervention Psych

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Aim The evidence of the effectiveness and cost‐effectiveness of early intervention for psychosis (EIP) services has motivated their implementation worldwide. However, complex interventions of such EIP services require local adaptations to successfully match population needs and cultural differences. Latin America is a heterogenous region where EIP services are progressively being adopted. Our aim is to map such initiatives in the region with a focus on implementation outcomes. Methods A scoping review following the Preferred Reporting Items for Systematic review and Meta‐Analysis extension for Scoping Reviews guidelines was conducted. International and regional databases were searched for publications describing EIP programmes in the region. Besides mapping the services, we described implementation outcomes based on the Standards for Reporting Implementation Studies Checklist. Results Ten articles describing seven EIP initiatives from the region were found. Four countries were represented: Argentina, Brazil, Chile and Mexico. The implementation outcomes reporting was heterogenous, although it was possible to ascertain EIP services are feasible and adequate for the region's context. Also, there is some evidence of effectiveness in terms of reducing hospitalizations and improving symptoms. Information about fidelity measures was scarce and there was no information about costs or cost‐effectiveness. Conclusions Only a small proportion of Latin American countries have adopted EIP services. Although these programmes seem to be feasible and effective, data on other implementation outcomes, such as fidelity, cultural appropriateness, cost‐effectiveness and affordability are not available. This might in part explain why this effective approach has not been yet scaled‐up at nationwide levels.

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Section: Introductionmentioning

confidence: 99%

Implementation of early psychosis services in Latin America: A scoping review

Aceituno

Mena²,

Vera

et al. 2020

Early Intervention Psych

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“…Volumetric analyses of the human hippocampus and hippocampal formation were initially performed retrospectively, and some of these studies identified volume reductions in adolescent, adult and ageing individuals who had experienced early-life adversity [161][162][163] . However, retrospective studies in specific populations are susceptible to confounding 100,164 , and later studies failed to replicate these findings 165,166 . More recently, prospective approaches have aimed to clarify the relationship between early-life adversity and imaging measures of brain circuit development 110,167 .…”

Section: Potential Mechanismsmentioning

confidence: 99%

Early-life adversity and neurological disease: age-old questions and novel answers

2019

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Neurological illnesses, including cognitive impairment, memory decline and dementia, affect over 50 million people worldwide, imposing a substantial burden on individuals and society. These disorders arise from a combination of genetic, environmental and experiential factors, with the latter two factors having the greatest impact during sensitive periods in development. In this Review , we focus on the contribution of adverse early-life experiences to aberrant brain maturation, which might underlie vulnerability to cognitive brain disorders. Specifically , we draw on recent robust discoveries from diverse disciplines, encompassing human studies and experimental models. These discoveries suggest that early-life adversity , especially in the perinatal period, influences the maturation of brain circuits involved in cognition. Importantly , new findings suggest that fragmented and unpredictable environmental and parental signals comprise a novel potent type of adversity , which contributes to subsequent vulnerabilities to cognitive illnesses via mechanisms involving disordered maturation of brain 'wiring'.

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“…Nowadays, the environment is in the spotlight of not only companies but also academic researches (Argacha et al, 2018;Barr-Anderson et al, 2018;Crossley et al, 2018). Therefore, both academics and companies search for useful methods for considering environmental aspects.…”

Section: Introductionmentioning

confidence: 99%

A decision-support approach under uncertainty for evaluating reverse logistics capabilities of healthcare providers in Iran

Yazdi

Hanne

Bottani

2020

JEIM

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PurposeThis paper aims to assess and prioritize manufacturing companies in the healthcare industry based on critical success factors (CSFs) of their reverse logistics (RL). The research involves seven medical device companies located in the Tehran Province, Iran.Design/methodology/approachTo identify and prioritize companies based on CSFs of RL, the study proposes a three-phase decision-making framework that integrates the Delphi method, the best-worst method (BWM) and the Additive Ratio Assessment (ARAS) method with Z-numbers. The weights required for this method are obtained by a variant of the BWM based on Z-numbers, denoted as Z-numbers Best-Worst Method, or ZBWM. Since decision-makers face an uncertain environment, Z-numbers, which are a kind of fuzzy numbers, are applied.FindingsFirst, after customizing CSFs by the Delphi method and obtaining 15 CSFs of RL, these are ranked by the hybrid BWM-ARAS method with Z-numbers. Results reveal which company appears to perform best with respect to their RL implementations. Based on this result, healthcare device companies should choose the highest priority company based on the selected RL CSFs and results from using the BWM-ARAS method with Z-numbers.Originality/valueThe contribution of this paper is using a hybrid ARAS-BWM method based on Z-numbers. Each of these methods has some merits compared to other similar methods. The combination of these methods contributes a new approach for prioritizing companies based on RL CSFs with high accuracy and reliability.

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Imaging Social and Environmental Factors as Modulators of Brain Dysfunction: Time to Focus on Developing Non-Western Societies

Cited by 14 publications

References 89 publications

Implementation of early psychosis services in Latin America: A scoping review

Implementation of early psychosis services in Latin America: A scoping review

Early-life adversity and neurological disease: age-old questions and novel answers

A decision-support approach under uncertainty for evaluating reverse logistics capabilities of healthcare providers in Iran

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