Imaging Procedure and Clinical Studies of [18F]FP-CIT PET

Abstract

N-3-[ 18 F]fluoropropyl-2β-carbomethoxy-3β-4-iodophenyl nortropane ([ 18 F]FP-CIT) is a radiopharmaceutical for dopamine transporter (DAT) imaging using positron emission tomography (PET) to detect dopaminergic neuronal degeneration in patients with parkinsonian syndrome. [ 18 F]FP-CIT was granted approval by the Ministry of Food and Drug Safety in 2008 as the inaugural radiopharmaceutical for PET imaging, and it has found extensive utilization across numerous institutions in Korea. This review article presents an imaging procedure for [ 18 F]FP-CIT PET to aid nuclear medicine physicians in clinical practice and systematically reviews the clinical studies associated with [ 18 F]FP-CIT PET.