Imaging of Thymic Epithelial Neoplasms

Rosado-de-Christenson, Melissa L.; Strollo, Diane C.; Marom, Edith M.

doi:10.1016/j.hoc.2008.03.011

Cited by 72 publications

(29 citation statements)

References 38 publications

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“…Intravenous contrast material should be administered unless significant contraindications are present, such as severe contrast agent allergy or renal failure, to adequately evaluate the vascular structures for evidence of invasion. Direct signs of vascular involvement include irregularity of the vessel lumen contour, encasement or obliteration of vessels, and endoluminal soft tissue, which can extend into cardiac chambers (32). Invasion of the adjacent lung parenchyma is rarely identified at multidetector CT and is typically detected at surgery.…”

Section: Multidetector Ctmentioning

confidence: 99%

IASLC/ITMIG Staging System and Lymph Node Map for Thymic Epithelial Neoplasms

et al. 2017

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Thymic epithelial neoplasms are rare malignancies that arise from the thymus and include thymoma, thymic carcinoma, and thymic neuroendocrine tumors. At least 15 different stage classifications have been proposed for thymic epithelial neoplasms and used to varying degrees in clinical practice, many of which have been constructed from small groups of patients. Traditionally, the Masaoka and Masaoka-Koga staging systems have been the schemes most commonly employed, and the latter has been recommended for use by the International Thymic Malignancy Interest Group (ITMIG). An official, consistent stage classification system has recently been recognized by the American Joint Committee on Cancer (AJCC) and the Union for International Cancer Control (UICC), which are responsible for defining stage classifications for neoplasms. To establish this stage classification system, the International Association for the Study of Lung Cancer (IASLC) and ITMIG amassed a large retrospective database and evaluated this group of cases to develop proposals for the eighth edition of the stage classification manuals. For this endeavor, IASLC provided funding and statistical analysis and ITMIG provided the involvement of the clinicians and researchers actively participating in the study of thymic epithelial neoplasms. To accomplish this, a Thymic Domain of the Staging and Prognostic Factors Committee (TD-SPFC) was established to formulate the rationale, methodology, and definitions of this tumor-node-metastasis (TNM) staging system, which is presented in this article. RSNA, 2017.

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Section: Multidetector Ctmentioning

confidence: 99%

IASLC/ITMIG Staging System and Lymph Node Map for Thymic Epithelial Neoplasms

et al. 2017

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“…In the setting of a large anterior mediastinal mass with features such as heterogeneity, local invasion, lymphadenopathy, and pleural effusion, thymic epithelial neoplasms other than thymoma such as thymic carcinoma ( Figure 5B) and carcinoid should be considered. 29 On 18 F-FDG PET/CT, thymic carcinomas and carcinoids typically demonstrate greater FDG uptake than thymomas. 30,31 In patients with enlarged lymph nodes or lobulated soft tissue masses in the mediastinum on cross-sectional imaging, which may or may not be seen in association with lymphadenopathy in the lower neck or axilla, a lymphoma such as Hodgkin disease and mediastinal large cell non-Hodgkin lymphoma should be considered.…”

Section: Lesions Identifiable By a Combination Of Imaging And Clinicamentioning

confidence: 99%

Approaching the Patient with an Anterior Mediastinal Mass: A Guide for Radiologists

Carter

Okumura

Detterbeck

et al. 2014

Journal of Thoracic Oncology

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Mediastinal masses are relatively uncommon, yet include a large variety of entities. Some tumors can be diagnosed with confidence based on imaging alone; others when a typical appearance is combined with the right clinical presentation. A structured approach for radiologists is presented to facilitate evaluation of patients with anterior mediastinal tumors. The approach focuses first on the more common tumors and on imaging features that strongly suggest a particular diagnosis. Discussion with the clinician can be very helpful in formulating a presumptive diagnosis. This article also discusses that confirmatory imaging or biopsy tests are most beneficial in particular situations.

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“…Different imaging modalities have been used for assessment of thymic epithelial tumors (1,(7)(8)(9)(10). Computed tomographic (CT) imaging is commonly used to assess thymic epithelial tumors, Implication for Patient Care n Diffusion MR imaging is a fast sequence that can be readily implemented with commercially available MR imagers and enables noninvasive assessment of thymic epithelial tumors in conjunction with routine MR imaging findings.…”

Section: Patientsmentioning

confidence: 99%