Imaging of peripheral nerve sheath tumors with pathologic correlation

Pilavaki, Mayia; Chourmouzi, Danai; Kiziridou, Anastasia; Skordalaki, A.; Zarampoukas, Thomas; Drevelengas, Antonios

doi:10.1016/j.ejrad.2003.12.001

Cited by 289 publications

(211 citation statements)

References 20 publications

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“…Los neurofibromas, a diferencia de los schwannomas, no solo crecen de las células de Schwann; estos están compuestos por una mezcla de células que incluye las perineurales, las de Schwann y los fibroblastos, intercaladas con fibras nerviosas, hebras de colágeno y matriz mixoide (12). En general, los neurofibromas son lesiones focales, bien definidas, de crecimiento lento, no encapsuladas y que comprometen las raíces, los troncos o los plexos nerviosos (13).…”

Section: Discussionunclassified

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Neurofibroma del hipogloso en un niño colombiano. Reporte de caso

et al. 2018

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REPORTE DE CASO | Resumen |Se presenta el caso de un paciente masculino de 14 años de edad, con antecedente de dos intervenciones quirúrgicas debidas a la presencia de una masa a nivel sublingual -la primera a los 8 meses de edad y la segunda a los 13 años-y sin información de estudios histopatológicos. Cerca de 8 meses después de la última intervención quirúrgica es valorado por el Servicio de Cirugía Maxilofacial de la Fundación Hospital Pediátrico de La Misericordia en Bogotá D.C., Colombia, por crecimiento acelerado de la misma lesión y por problemas en la deglución y el lenguaje. En la revisión del paciente se encuentra una masa importante sublingual, dificultad en el lenguaje, deformidad mandibular y alteraciones en la mordida, por lo que se decide intervenir quirúrgicamente de nuevo. El resultado de la biopsia es un tumor mesenquimal benigno característico de neurofibroma, que por su ubicación sugiere probable compromiso del nervio hipogloso.Palabras clave: Neurofibroma; Nervio hipogloso; Neoplasia (DeCS).

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Section: Discussionunclassified

“…La RMN es la modalidad más útil, ya que permite determinar si la masa es extrínseca o intrínseca al nervio y si hay compromiso de estructuras adyacentes; en T1 el neurofibroma mostró una intensidad de señal baja y en T2 fue hiperintenso con una región hipointensa central característica (colágeno y tejido fibroso) (12).…”

Section: Discussionunclassified

Neurofibroma del hipogloso en un niño colombiano. Reporte de caso

et al. 2018

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“…PN is characterized with tumoral enlargement in a long nerve segment with nodular components resulting in the gross pathologic appearance resembling "bag of worms" 12,13 . It is often difficult for a correct diagnosis to be made before surgical procedure because there are no characteristic clinical and laboratory findings, including tumor markers and imaging methods that distinguish PN from other neoplasms 14,15 .…”

Section: Discussionmentioning

confidence: 99%

A rare location for an infrequent tumor: Plexiform neurofibroma in hepatic hilum

et al. 2015

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SUMMARYPlexiform neurofibroma is frequently encountered in association with NF-1 but still can be seen as solitary lesions. While disease mostly involves extremities a very rare site of involvement is hepatic hilum. This paper reports a case of a 58 year old female patient with solitary plexiform neurofibroma located in the hepatoduodenal region which successfully treated by surgical procedure. Keywords: Plexiform neurofibroma, neurofibromatosis, hepatic hilum ÖZETPleksiform nörofibroma sıklıkla NF-1 ile birlikte karşılaşılan ancak soliter olarak ta gözlenebilen lezyonlardır. Hastalık genellikle ekstremiteleri ilgilendirirken hepatik hilum çok nadir bir tutulum bölgesidir. Bu yazı, cerrahi prosedür ile başarılı şekilde tedavi edilmiş, hepatoduodenal bölgede lokalize, pleksiform nörofibroma lezyonu olan 58 yaşındaki kadın bir vakayı sunmaktadır.

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“…Even the initial description by Varma et al 45 identified it in only 12 (52%) of 23 BPNSTs. 4,34,37,38 Inhomogeneity in MPNSTs seems to reflect coexisting areas of hypo-and hypercellularity rather than regressive changes like necrosis or hemorrhage. 33,44 Initial efforts to discern neurofibromas and plexiform neurofibromas from MPNSTs have been successful recently with the use of FDG-PET.…”

Section: Ambiguous Findingsmentioning

confidence: 99%

Nerve sheath tumor surgery: case-guided discussion of ambiguous findings, appropriateness of removal, repeated surgery, and nerve repairs

Kretschmer

Antoniadis

Heinen

et al. 2007

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✓In this article the authors attempt to raise awareness of the pitfalls and controversial issues in nerve tumor surgery. In a case-guided format, examples of ambiguous findings, inappropriate tumor removal, repeated surgery, and nerve repairs are provided. The authors also discuss the need to establish a correct diagnosis preoperatively and to avoid the erroneous identification of malignant peripheral nerve sheath tumors (MPNSTs). They emphasize that not all of the principles of soft tissue sarcoma treatment protocols are applicable to MPNST. A situation of repeated surgery for supposedly malignant tumor is described, and an outline of the indications for, and an approach to, repair after lesion removal is given.

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Imaging of peripheral nerve sheath tumors with pathologic correlation

Cited by 289 publications

References 20 publications

Neurofibroma del hipogloso en un niño colombiano. Reporte de caso

Neurofibroma del hipogloso en un niño colombiano. Reporte de caso

A rare location for an infrequent tumor: Plexiform neurofibroma in hepatic hilum

Nerve sheath tumor surgery: case-guided discussion of ambiguous findings, appropriateness of removal, repeated surgery, and nerve repairs

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