Imaging of Metastatic Disease to the Ovary/Adnexa

Roseland, Molly E.; Millet, John D.; Wasnik, Ashish P.

doi:10.1016/j.mric.2022.06.005

Cited by 2 publications

(2 citation statements)

References 87 publications

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“…No clear differences between primary and metastatic ovarian tumors have been drawn from the current imaging reports [9]. However, imaging examination has certain diagnostic signi cance for ovarian metastatic tumors.First, imaging examination can detect lesions outside the accessory area, thus increasing the diagnosis of metastatic ovarian cancer.Preoperative US, CT, and PET-CT can evaluate the disease progression and provide guidance for treatment.Secondly,it has been reported that the metastatic ovarian cancer is usually bilateral and is more common on the right side [2].Therefore, when bilateral tumors are found, other organs are often examined to determine the presence of a primary malignancy.In addition, metastatic ovarian cancer often presents as solid mass or mixed cystic mass, while primary ovarian tumor often presents as cystic mass or with lique ed necrosis area [10].The imaging of our case showed a solid main mass, which is different from the primary ovarian cancer.While it appears as a unilateral ovarian mass, which increases the di culty of diagnosis.The patient's imaging ndings are useful for showing systemic metastasis,but specifc characteristics are lacking.So we chose a real-time CEUS-guided needle biopsy to identify the primary lesion.Needle biopsy may be conclusive in such a clinical situation as the case in diagnosing.…”

Section: Discussionmentioning

confidence: 97%

“…The krukenberg tumor is a rare metastatic ovarian malignancy, and the most tumors originate from the gastrointestinal tract,such as stomach, and colon. However cases originating form gallbladder or hepatic bile duct are little known [1].These metastatic tumors are usually bilateral,few cases can seen unilaterally [2].We reported a rare case that presents as an metastatic right-ovarian malignancy of gallbladder origin and share our analysis of imaging ndings,diagnosis,and treatment methods.…”

Section: Introductionmentioning

confidence: 92%

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Real-time contrast enhanced ultrasound-guided percutaneous biopsy in diagnosing gallbladder carcinoma metastasising to the ovaries:a case report

Wang

Liu

Liang

et al. 2023

Preprint

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Introduction：Multiple-organ primary tumors can invade the ovary through lymphatic and hematogenous routes presenting as ovarian Krukenberg tumors (KT);however they rarely originate from the gallbladder and are often present as primary ovarian tumors;however,their treatments are totally different. Patient concerns:A 62-year-old Chinese woman presented with abdominal distension for Six months and a weight loss of 5 kg for two months. Diagnoses: Base on multiple imaging examinations,the patient was preliminarily diagnosed with a malignant tumor of unknown origin with multiple metastases(liver,gallbladder,right-adnexal,omentum).To identify the origin of the malignancy,the patient received real-time contrast enhanced ultrasound-guided (CEUS-guided) percutaneous biopsy.The postsurgical pathologic examination showed perihepatic hypoecho and right-adnexal mass were both metastatic adenocarcinoma from the gallbladder. Interventions: The patient received chemotherapy with gemcitabine and cisplatin instead of surgery,however,after six cycles, the lesion increased after reexamination, so the treatment was changed to combination with duvariumab regimen for 5 cycles. Outcomes:At present, the treatment process went smoothly with no recurrence or obvious progress during follow-up. Conclusions: Differential diagnosis between primary and metastatic ovarian tumors is important.Early diagnosis and effective treatment options are essential for patient survival.The punch biopsy is significant for patients with multiple metastases that cannot tolerate surgery. Ethical compliance: All procedures performed in studies involving human participants comply with the ethical standards of the institutional and / or national research committees and with the 1964 Helsinki Declaration and its later amendments or similar ethical standards. Data Access Statement: The research data supporting this publication is available from the NN repository at www.NNN.org/download/

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Section: Discussionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 92%

Real-time contrast enhanced ultrasound-guided percutaneous biopsy in diagnosing gallbladder carcinoma metastasising to the ovaries:a case report

Wang

Liu

Liang

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

Real-time contrast-enhanced ultrasound-guided percutaneous biopsy in the diagnosis of ovarian metastasis of gallbladder carcinoma: a case report

et al. 2023

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Background Multiple-organ primary tumors can invade the ovary through lymphatic and hematogenous routes, presenting as ovarian Krukenberg tumors, but these rarely originate from the gallbladder. Krukenberg tumors can present similar to primary ovarian tumors; however, their treatments are completely different. Patient concerns A 62-year-old Chinese woman presented with abdominal distension for six months and weight loss of five kilograms for two months. Diagnoses Based on multiple imaging examinations, the patient was preliminarily diagnosed with a malignant tumor of unknown origin with multiple metastases (omentum). To identify the origin of the malignancy, the patient underwent real-time contrast-enhanced ultrasound-guided percutaneous biopsy. The results revealed a perihepatic hypoechoic lesion and right adnexal mass that were both metastatic adenocarcinomas from the gallbladder. Interventions The patient initially received chemotherapy with gemcitabine and cisplatin instead of surgery. However, the tumor increased in size on re-examination after two cycles, so the treatment was shifted to a combination regimen with durvalumab for six cycles. Outcomes The treatment proceeded smoothly, with no recurrence or obvious progression of the cancer during follow-up. Conclusions Differentiating between primary and metastatic ovarian tumors is important. Early diagnosis and effective treatment options are essential for patient survival. CEUS-guided percutaneous biopsy is a valuable procedure for patients with multiple metastases who cannot tolerate surgery.

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Imaging of Metastatic Disease to the Ovary/Adnexa

Cited by 2 publications

References 87 publications

Real-time contrast enhanced ultrasound-guided percutaneous biopsy in diagnosing gallbladder carcinoma metastasising to the ovaries:a case report

Real-time contrast enhanced ultrasound-guided percutaneous biopsy in diagnosing gallbladder carcinoma metastasising to the ovaries:a case report

Real-time contrast-enhanced ultrasound-guided percutaneous biopsy in the diagnosis of ovarian metastasis of gallbladder carcinoma: a case report

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