Imaging of metabolic and overload disorders in tissues and organs

Bruno, Federico; Albano, Domenico; Agostini, Andrea; Benenati, Massimo; Cannella, Roberto; Cellina, Michaela; Cozzi, Diletta; Danti, Ginevra; Muzio, Federica De; Gentili, Francesco; Giacobbe, Giuliana; Gitto, Salvatore; Grazzini, Giulia; Grazzini, Irene; Messina, Carmelo; Palmisano, Anna; Palumbo, Pierpaolo; Bruno, Alessandra; Grassi, Francesca; Grassi, Roberta; Fusco, Roberta; Granata, Vincenza; Giovagnoni, Andrea; Miele, Vittorio; Barile, Antonio

doi:10.1007/s11604-022-01379-7

Cited by 4 publications

(2 citation statements)

References 213 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The regulation of these iron ion-containing molecules is tightly controlled as their dysregulation may be harmful to human health [12,[25][26][27][28][29][30], as heme also appears to have toxic properties [31]. Further evidence for the tight regulation of iron ions during pregnancy [32], exercise [33], and hypoxia [34] indicate that this ion is very important biologically.…”

Section: Incorporation Of Ferro-magnetic Ions In Essential Systems An...mentioning

confidence: 99%

The Influence of Magnetic Fields, Including the Planetary Magnetic Field, on Complex Life Forms: How Do Biological Systems Function in This Field and in Electromagnetic Fields?

Hart

2024

Biophysica

View full text Add to dashboard Cite

Life on Earth evolved to accommodate the biochemical and biophysical boundary conditions of the planet millions of years ago. The former includes nutrients, water, and the ability to synthesize other needed chemicals. The latter includes the 1 g gravity of the planet, radiation, and the geomagnetic field (GMF) of the planet. How complex life forms have accommodated the GMF is not known in detail, considering that Homo sapiens evolved a neurological system, a neuromuscular system, and a cardiovascular system that developed electromagnetic fields as part of their functioning. Therefore, all of these could be impacted by magnetic fields. In addition, many proteins and physiologic processes utilize iron ions, which exhibit magnetic properties. Thus, complex organisms, such as humans, generate magnetic fields, contain significant quantities of iron ions, and respond to exogenous static and electromagnetic fields. Given the current body of literature, it remains somewhat unclear if Homo sapiens use exogenous magnetic fields to regulate function and what can happen if the boundary condition of the GMF no longer exerts an effect. Proposed deep space flights to destinations such as Mars will provide some insights, as space flight could not have been anticipated by evolution. The results of such space flight “experiments” will provide new insights into the role of magnetic fields on human functioning. This review will discuss the literature regarding the involvement of magnetic fields in various normal and disturbed processes in humans while on Earth and then further discuss potential outcomes when the GMF is no longer present to impact host systems, as well as the limitations in the current knowledge. The GMF has been present throughout evolution, but many details of its role in human functioning remain to be elucidated, and how humans have adapted to such fields in order to develop and retain function remains to be elucidated. Why this understudied area has not received the attention required to elucidate the critical information remains a conundrum for both health professionals and those embarking on space flight. However, proposed deep space flights to destinations such as Mars may provide the environments to test and assess the potential roles of magnetic fields in human functioning.

show abstract

Section: Incorporation Of Ferro-magnetic Ions In Essential Systems An...mentioning

confidence: 99%

The Influence of Magnetic Fields, Including the Planetary Magnetic Field, on Complex Life Forms: How Do Biological Systems Function in This Field and in Electromagnetic Fields?

Hart

2024

Biophysica

View full text Add to dashboard Cite

show abstract

“…The regulation of these Fe-containing molecules is tightly controlled as their dysregulation may be harmful to human health [12,[25][26][27][28][29][30] as heme appears to have toxic properties [31]. Further evidence for the tight regulation of iron during pregnancy [32], exercise [33], and hypoxia [34] indicate that this ion is very important biologically.…”

Section: Incorporation Of Ferro-magnetic Ions In Essential Systems An...mentioning

confidence: 99%

The Influence of Magnetic Fields including the Geomagnetic Field of Earth on Complex Life Forms: A Silent “Partner” in Human Health and Disease?

Hart

2023

Preprint

View full text Add to dashboard Cite

Life on Earth evolved to accommodate the biochemical and biophysical boundary conditions of the planet millions of years ago. The former includes nutrients, water, and ability to synthesize other needed chemicals. The latter include the 1 g gravity of the planet, radiation, and the geomagnetic field (GMF)of the planet. How complex life forms have accommodated the GMF is not known in detail considering that Homo sapiens evolved a neuro system and a cardiovascular system that develops electromagnetic fields as part of their functioning. In addition, many proteins and physiologic processes utilize Fe ions, an ion that exhibits magnetic properties. Thus, complex organisms such as current humans generate magnetic fields, contain significant quantities of the Fe ion, and also respond to exogenous-supplied static and electromagnetic fields. Whether humans can store information in self-generated magnetic fields remains to be determined. Given the current body of literature, it remains somewhat unclear how Homo sapiens use exogenous magnetic fields to regulate function, and what can happen if the boundary condition of the GMF of Earth is no longer exerting an effect. Proposed deep space flights to destinations such as Mars will provide some insights as space flight could not have been anticipated by evolution. The results of such space flight “experiments” will provide new insights in the role of magnetic fields on human functioning. The outcomes may also have implications for those on Earth as magnetic field influences may play a role in developmental conditions such as autism and senescence-associated conditions such as dementia when integration of the biological and biophysical aspects of humans of humans are required for effective functioning. This review will discuss the involvement of magnetic fields on various normal and disturbed processes in humans while on Earth and then further discuss potential outcomes when the GMF is no longer available to impact host systems. Thus, the GMF of the Earth has been present throughout evolution but details of its role in human functions still remain to be elucidated.

show abstract

Metabolic Disorders

Plotkin,

Davis

2023

Musculoskeletal Imaging

View full text Add to dashboard Cite

Imaging of metabolic and overload disorders in tissues and organs

Cited by 4 publications

References 213 publications

The Influence of Magnetic Fields, Including the Planetary Magnetic Field, on Complex Life Forms: How Do Biological Systems Function in This Field and in Electromagnetic Fields?

The Influence of Magnetic Fields, Including the Planetary Magnetic Field, on Complex Life Forms: How Do Biological Systems Function in This Field and in Electromagnetic Fields?

The Influence of Magnetic Fields including the Geomagnetic Field of Earth on Complex Life Forms: A Silent “Partner” in Human Health and Disease?

Metabolic Disorders

Contact Info

Product

Resources

About