Imaging of granulomatous and chronic invasive fungal sinusitis: Comparison with allergic fungal sinusitis

Reddy, C. Ekambar Eshwara; Gupta, Ashok; Singh, Paramjit; Mann, S. B. S.

doi:10.1016/j.otohns.2010.02.027

Cited by 60 publications

(28 citation statements)

References 19 publications

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“…Patients are usually only mildly immunocompromised (eg, diabetes or corticosteroid therapy) [38] and the disease has also been reported in immunocompetent patients [39].…”

Section: Clinical Presentationmentioning

confidence: 99%

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Fungal Rhinosinusitis: A Radiological Review with Intraoperative Correlation

et al. 2017

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The interaction between fungi and the sinonasal tract results in a range of clinical presentations with a broad spectrum of clinical severity. The most commonly accepted classification system divides fungal rhinosinusitis into invasive and noninvasive subtypes based on histopathological evidence of tissue invasion by fungi. Invasive fungal rhinosinusitis is subdivided into acute invasive and chronic invasive categories. The chronic invasive category includes a subcategory of chronic granulomatous disease. Noninvasive fungal disease includes localized fungal colonization, fungal ball, and allergic fungal rhinosinusitis. Noninvasive disease is simply fungal material (or the products of the inflammatory reaction of the sinus mucosa) that fills the sinuses but does not invade tissue. Bone loss is related to expansion of the sinus(es). Invasive disease causes tissue destruction, such that it expands past the bony confines of the sinuses. It can rapidly spread, causing acute necrosis. Alternatively, there may be slow tissue invasion characterized by symptoms confused with normal sinusitis, but destruction of normal nasal and paranasal structures.

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“…Patients are usually only mildly immunocompromised (eg, diabetes or corticosteroid therapy) [38] and the disease has also been reported in immunocompetent patients [39].…”

Section: Clinical Presentationmentioning

confidence: 99%

“…The affected sinus is not significantly expanded and bony erosion is localized to the site of extra-sinus extension ( Figure 6B) [38].…”

Section: Imaging Featuresmentioning

confidence: 99%

Fungal Rhinosinusitis: A Radiological Review with Intraoperative Correlation

et al. 2017

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“…Mineralization was considered to be present when the focal high-density area was higher and closer to the discrete bone density according to CT attenuation. 8,9 Group 2 showed high-density secretion without mineralization ( Fig. 2).…”

Section: Ct Analysismentioning

confidence: 96%

Hyperdense findings in sinus computed tomography of chronic rhinosinusitis

Wang

Tsai

et al. 2015

Int Forum Allergy Rhinol

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“…The complications of chronic fungal invasive infections are similar to AFIFRS, and the duration might prompt the clinician to consider a differential diagnosis of malignancy. Reddy et al [14]. studied 17 cases of chronic invasive fungal sinusitis which were differentiated on histopathology into 15 cases of granulomatous invasive fungal sinusitis and 2 cases of chronic invasive fungal sinusitis, and they demonstrated homogeneity with no focal hyperattenuation and localized bony erosion at the site of the extrasinus expansion of the fungal lesion.…”

Section: Chronic Invasive Fungal Rhinosinusitis and Chronic Granulomamentioning

confidence: 99%

A Radiological Profile of Fungal Sinusitis

Pillai

Bhandarkar

Jha

et al. 2017

Asian J Pharm Clin Res

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Objectives: To create a radiological profile of fungal sinusitis and determine the radiological differences between fungal and nonfungal sinusitis based on the presence of hyperattenuation, bony erosion, neo-osteogenesis, air-fluid level, and extrasinus extension.Methods: This is a retrospective, single-blind, case-control study involving the analysis of 119 computed tomography (CT) scans of the paranasal sinuses. Based on the histopathology, they were divided into cases comprising fungal sinusitis and controls of nonfungal sinusitis. Benign and malignant tumors and previously operated cases of fungal sinusitis were excluded from the study. The principal investigators were blinded to the diagnosis. The comparison parameters were hyperattenuation, the presence of air-fluid level, bone erosion, neo-osteogenesis, and extrasinus extension. Data was analyzed by Chi-square and Fischer exact t-test using SPSS 14.0 software and a p < 0.05 was considered significant. Results:Our study showed the presence of hyperattenuation, neo-osteogenesis, bone erosion, air-fluid level, extrasinus extension in 75.2%, 48.3%, 25.9%, 36.2%, and 6.9% of the cases and 13.1%, 16.4%, 6.6%, 9.8%, and 0 controls, respectively. All the parameters were statistically significant in cases when compared to controls. Conclusion:Hyperattenuation, neo-osteogenesis, air-fluid level, bone erosion, and extrasinus extension are the parameters on CT imaging that will help routinely assess and differentiate fungal sinusitis from nonfungal sinusitis with considerable accuracy, although, there is an overlap with malignancy when the parameter of bone erosion is considered as a differential diagnosis of chronic invasive fungal sinusitis. It reiterates the fact that history, clinical examination, and laboratory evaluation hold an important role in provisional diagnosis.

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Imaging of granulomatous and chronic invasive fungal sinusitis: Comparison with allergic fungal sinusitis

Abstract: Radiological features of IFS are described that are different from AFS.

Cited by 60 publications

References 19 publications

Fungal Rhinosinusitis: A Radiological Review with Intraoperative Correlation

Fungal Rhinosinusitis: A Radiological Review with Intraoperative Correlation

Hyperdense findings in sinus computed tomography of chronic rhinosinusitis

A Radiological Profile of Fungal Sinusitis

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