Imaging of Gastric Carcinomatosis

Martínez, Raquel Saiz; Dromain, Clarisse; Violi, Naïk Vietti

doi:10.3390/jcm10225294

Cited by 10 publications

(10 citation statements)

References 74 publications

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“…Interactively reading the coronal and sagittal planes in addition to the mere axial plane can improve the visualization and localization of PM lesions ( 22 ). Some studies have demonstrated that the additional interpretation of coronal and sagittal planes could improve the detection of lesions on the perihepatic visceral peritoneum and superior parietal peritoneum, which run horizontally ( 12 , 16 , 22 ). The sagittal plane can provide a clear section view of the GCL extending to the transverse colon ( 16 , 22 , 31 ).…”

Section: Discussionmentioning

confidence: 99%

“…Some studies have demonstrated that the additional interpretation of coronal and sagittal planes could improve the detection of lesions on the perihepatic visceral peritoneum and superior parietal peritoneum, which run horizontally ( 12 , 16 , 22 ). The sagittal plane can provide a clear section view of the GCL extending to the transverse colon ( 16 , 22 , 31 ). One study also described the improvement in sensitivity from 64% in axial planes to 82% in MPR images during the PM diagnosis ( 12 ).…”

Section: Discussionmentioning

confidence: 99%

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CT characteristics for predicting prognosis of gastric cancer with synchronous peritoneal metastasis

Liu²,

Sun³

et al. 2023

Front. Oncol.

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IntroductionTo explore the CT characteristics for the prediction of long term survival in gastric cancer patients with synchronous peritoneal metastasis (PM).Materials and methodsSixty-six patients diagnosed as gastric cancer with synchronous peritoneum metastasis were enrolled in this retrospective study. Ten anatomic peritoneal regions were evaluated to check for the signs of PM on CT. One positive area equaled one score. The CT characteristic-based PM score (CT-PMS) was the sum of the total points assigned to all 10 regions, with a range of 0–10. The triple tract dilatation (TTD) sign caused by peritoneal metastasis, the presence of extensive lymph node metastasis (ELM), and the grade of ascites were recorded. The overall survival (OS) was used as the prognostic indicator. The performance of the CT characteristics was assessed by the Kaplan–Meier analysis and Cox proportional hazards model, while its reproducibility was evaluated by Kappa statistic and weighted Kappa statistic.ResultsPatients with a CT-PMS of 3–10 had significantly poorer OS (P = .02). Patients with either the presence of TTD sign, or ELM had a trend toward unfavorable OS (both P = .07), and when CT-PMS of 3–10 was detected simultaneously, the survival was further reduced (P = .00 for TTD sign; P = .01 for ELM). The grade of ascites failed to show a significant correlation with OS. The interobserver reproducibility for assessing the CT-PMS, the presence of TTD sign, the presence of ELM, and the grade of ascites had a substantial to almost perfect agreement.ConclusionThe prognosis of gastric cancer patients with PM has a correlation with the extent of metastasis dissemination on baseline CT. A CT-PMS of 3–10 is associated with a worse prognosis than that of 0–2. The presence of TTD sign and ELM may help further select patients with extraordinarily poor prognoses.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

CT characteristics for predicting prognosis of gastric cancer with synchronous peritoneal metastasis

Liu²,

Sun³

et al. 2023

Front. Oncol.

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“…However, it has limited soft tissue contrast, which limits its ability to visualize small peritoneal metastases (PM), especially when adjacent to bowel structures or the mesentery, limiting its sensitivity in detecting lesions and its accuracy in staging PM, as it underestimates the results compared with the surgical Peritoneal Cancer Index (PCI). For this reason, laparoscopy remains the reference for PC staging [ 39 ].…”

Section: Diagnostic Techniquesmentioning

confidence: 99%

Imaging in Gastric Cancer: Current Practice and Future Perspectives

et al. 2023

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Gastric cancer represents one of the most common oncological causes of death worldwide. In order to treat patients in the best possible way, the staging of gastric cancer should be accurate. In this regard, endoscopy ultrasound (EUS) has been considered the reference standard for tumor (T) and nodal (N) statuses in recent decades. However, thanks to technological improvements, computed tomography (CT) has gained an important role, not only in the assessment of distant metastases (M status) but also in T and N staging. In addition, magnetic resonance imaging (MRI) can contribute to the detection and staging of primary gastric tumors thanks to its excellent soft tissue contrast and multiple imaging sequences without radiation-related risks. In addition, MRI can help with the detection of liver metastases, especially small lesions. Finally, positron emission tomography (PET) is still considered a useful diagnostic tool for the staging of gastric cancer patients, with a focus on nodal metastases and peritoneal carcinomatosis. In addition, it may play a role in the treatment of gastric cancer in the coming years thanks to the introduction of new labeling peptides. This review aims to summarize the most common advantages and pitfalls of EUS, CT, MRI and PET in the TNM staging of gastric cancer patients.

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“…9 By observing the Brownian movement of water molecules indirectly, diffusion-weighted imaging (DWI) can qualitatively and quantitatively provide morphologic and functional information to distinguish benign from malignant lesions. 10 Although MRI improved the accuracy of TNM staging for AGC, MRI alone is insufficient for establishing a prognostic indicator of OS. 11 As an emerging field, radiomics has been used to convert qualitative images to quantitative data using a large series of automatically extracted data-characterization algorithms.…”

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confidence: 99%

Risk Stratification and Overall Survival Prediction in Advanced Gastric Cancer Patients Based on Whole‐Volume MRI Radiomics

Chen

Gao

et al. 2023

Magnetic Resonance Imaging

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BackgroundThe prognosis of advanced gastric cancer (AGC) patients has attracted much attention, but there is a lack of evaluation method. MRI‐based radiomics has the potential to evaluate AGC patients' prognosis.PurposeTo identify and validate the risk stratification and overall survival (OS) in AGC patients using MRI‐based radiomics.Study TypeRetrospective.SubjectsA total of 233 patients (168 males, 63.6 ± 11.1 years; 65 females, 59.7 ± 11.8 years) confirmed AGC were collected. The data were randomly divided into a training (164) and validation set (69).SequenceA 3.0 T, axial T2‐weighted, diffusion‐weighted imaging, and contrast‐enhanced T1‐weighted (CE‐T1WI).AssessmentRadiologist 1 segmented 233 patients and radiologist 2 segmented randomly 50 patients on CE‐T1WI. The risk score (RS) was summed by each sample based on the radiomics features and correlation coefficients. Patients were followed up for 7–67 months (median 41; 138 dead and 95 alive).Statistical TestsThe intraclass correlation coefficient (ICC) and Kappa value were calculated. Differences in survival analysis were assessed by Kaplan–Meier curves and log‐rank test. Cox‐regression analysis was performed to identify the radiomics features and clinical indicators associated with OS. The calibration curves were built to assess the model. A two‐tailed P value < 0.05 was considered statistically significant.ResultsIntegrated with age, lymphovascular invasion (LVI) and RS, a survival combined model was built. The area under the curve (AUC) for predicting 3‐year and 5‐year OS was 0.765 and 0.788 in the training set, 0.757 and 0.729 in the validation set. There was no significant difference between the radiomics model and survival combined model for 3‐year (0.690 vs. 0.757, P = 0.425) and 5‐year OS (0.687 vs. 729, P = 0.412) in the validation set. The calibration curves showed a high degree of fit for the survival combined model.Data ConclusionThis study established a survival combined model that might help AGC patients in future clinical decision‐making.Evidence Level33Technical EfficacyStage 5

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Imaging of Gastric Carcinomatosis

Cited by 10 publications

References 74 publications

CT characteristics for predicting prognosis of gastric cancer with synchronous peritoneal metastasis

CT characteristics for predicting prognosis of gastric cancer with synchronous peritoneal metastasis

Imaging in Gastric Cancer: Current Practice and Future Perspectives

Risk Stratification and Overall Survival Prediction in Advanced Gastric Cancer Patients Based on Whole‐Volume MRI Radiomics

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