Abstract:This paper explores suitable conditions for the imaging of DNA molecules by atomic force microscope (AFM). As a typical biological macro-molecule, DNA with genetic information has attracted extensive attention, which is an important research subject in biomedicine. In this work, 3-Aminopropyl Triethyl Silane (APTES), Ni 2+ and Mg 2+ were used to modify the surface of mica substrate, and DNA molecules were adhered to the mica surface through the physical interaction of charges. The DNA molecules were imaged usi… Show more
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