Imaging of congenital genitourinary anomalies

Acharya, Patricia T.; Ponrartana, Skorn; Lai, Liangzhen; Vasquez, Evalynn; Goodarzian, Fariba

doi:10.1007/s00247-021-05217-2

Cited by 2 publications

(1 citation statement)

References 36 publications

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“…Here, UCAs are characterized as “any live-birth with a urinary or genital condition”. UCAs are often discovered in the prenatal or immediately postnatal period, with a substantial percentage being found in older children with varied degrees of severity 1 . UCAs often present as incontinence, recurrent urinary tract infections, atypical genitalia or other abdominal issues due to congenital anomalies of the urinary tract 2 .…”

Section: Introductionmentioning

confidence: 99%

Sex difference and risk factors in burden of urogenital congenital anomalies from 1990 to 2019

Huang,

Tang,

Chen

et al. 2023

Sci Rep

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Urogenital congenital anomalies (UCAs) is defined as “any live-birth with a urinary or genital condition” and affects millions of men and women worldwide. However, sex differences and related environmental risk factors in UCAs burden on a global scale have not been assessed. Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we estimated prevalence, incidence, mortality and disability-adjusted life years (DALYs) of UCAs from 1990 to 2019 by sex, region, and socio-demographic Index (SDI) in 204 countries and territories. The disease burden of UCAs was also estimated attributable to each risk factor were estimated according to risk exposure. In 2019, UCAs caused 10,200 all-ages deaths (95% UI 7550–13,400). The combined global incidence rate was 8.38 per 1000 (95% UI 5.88–12.0) live births. The ASIR increased slightly, while the ASDR decreased from 1990 to 2019.The UCAs burden varies greatly depending on the development level and geographical location. The UCAs burden was significantly higher in men than in women, and the sex differences showed an enlarging trend. Health risks and issues, including pollution, child and maternal malnutrition, diet habits, unsafe sanitation and water source, were detected to be positively related to UCAs burden. Albeit the age-standardised prevalence, mortality, incidence, and DALYs of UCAs have decreased, they still cause a public health challenge worldwide. The high deaths and DALYs rates in low and low-middle SDI countries highlight the urgent need for improved preventive, diagnostic, and therapeutic measures. Global strategies for enhancing water safety, reducing pollution, and healthy diets are crucial steps in reducing the burden of UCAs.

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Section: Introductionmentioning

confidence: 99%

Sex difference and risk factors in burden of urogenital congenital anomalies from 1990 to 2019

Huang,

Tang,

Chen

et al. 2023

Sci Rep

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“Feed-and-wrap” technique versus deep sedation for neonatal magnetic resonance imaging: a retrospective comparative study

Lollert,

Frey,

Hoffmann

et al. 2024

Eur Radiol

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Objectives Neonatal MRI is usually performed under deep sedation, which is challenging—especially in low-weight premature patients. In addition, long-term side effects, such as neurotoxicity, are of concern. An alternative to sedation is to induce natural sleep by feeding and immobilising the child, the “feed-and-wrap” technique (FWT). The objective of this study was to evaluate differences in image quality between neonates examined under sedation and by using the FWT during the first four months of life. Materials and methods We retrospectively assessed image quality (based on a 4-point semiquantitative scale) of all MRI examinations in neonates performed at our institution between July 2009 and August 2022. Differences in image quality between examinations under sedation versus FWT were evaluated. Results We included 432 consecutive patients, 243 (56%) using sedation and 189 (44%) using the FWT. Corrected age and body weight (mean ± SD: 3.7 ± 1.1 versus 4.5 ± 1.3 kg, p < 0.001) were significantly lower in the FWT group. The overall success rate in the FWT group was 95%. Image quality was slightly lower when using the FWT (mean ± SD: 3.7 ± 0.43 versus 3.96 ± 0.11, p < 0.001). Multivariate analysis showed a higher risk of acquiring sequences with diagnostic limitations in the FWT group (p < 0.001), increasing with corrected age (p = 0.048). Conclusion The FWT is a highly successful method to perform MRI scans in term and preterm neonates. Overall image quality is only slightly lower than under sedation. Especially in immature low-weight preterm patients, the FWT is a reliable option to perform MRI studies without exposing the child to risks associated with sedation. Clinical relevance statement The “feed-and-wrap” technique enables high-quality MRI examinations in neonates, including low-weight premature patients. Deep sedation for diagnostic MRI procedures in this age group, which has the risk of short- and long-term complications, can often be avoided. Key Points Deeply sedating neonates for MR examinations comes with risks. Image quality is only slightly lower when using the "feed-and-wrap" technique. The “feed-and-wrap” technique is feasible even in low-weight premature infants.

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Imaging of congenital genitourinary anomalies

Cited by 2 publications

References 36 publications

Sex difference and risk factors in burden of urogenital congenital anomalies from 1990 to 2019

Sex difference and risk factors in burden of urogenital congenital anomalies from 1990 to 2019

“Feed-and-wrap” technique versus deep sedation for neonatal magnetic resonance imaging: a retrospective comparative study

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