Safety and efficacy of pharmacological treatments for axial spondyloarthritisAxial spondyloarthritis (ax-SpA) is a chronic inflammatory rheumatic disease with a variety of clinical presentations including chronicbackpain,enthesitis,arthritis,anddactylitis.Occasionally, ax-SpApatientsmaypresentwithextra-articularmanifestations [1][2][3][4] including anterior uveitis, psoriasis, and inflammatory bowel disease (IBD). 5 The concept of ax-SpA includes both patients with definite structural damage on radiographs of the sacroiliac joints (according to 1984 New York criteria), (radiographic ax-SpA), and patients without structural damage, (non-radiographic ax-SpA).Non-radiographic ax-SpA is mostly considered an early stage of radiographic ax-SpA, but not all non-radiographic ax-SpA will develop structural damage in the axial skeleton.