Imaging in Pediatric Obstructive Jaundice

Jain, Rajiv; Gupta, Amit; Kandasamy, Devasenathipathy; Jana, Manisha

doi:10.1007/s12098-022-04171-7

Cited by 9 publications

(6 citation statements)

References 33 publications

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“…19,21 Another study reported the use of MR cholangiography (MRCP) and CT to predict the linear filling of the worm. 22 Whereas this study reported ERCP is a fundamental technique for the visualization, extraction, and therapeutic of biliary ascariasis.…”

Section: Discussionmentioning

confidence: 93%

“…According to previous studies when antimicrobial treatment is failing then endoscopic treatment was recommended by the clinics. 22,24 Previous studies also reported that the development of endoscopic diagnosis and treatment was used to remove or deworm the Ascariasis from the body. ERCP is a confirmation test to access the Ascariasis worms in the biliary tract and to visualize and treat the ascariasis.…”

Section: Discussionmentioning

confidence: 99%

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Untitled

2023

IJRRT

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Ascaris lumbricoides are familiar with the roundworm that causes biliary infections in humans. Nevertheless, ascariasis is primarily found in the jejunum and transferred in numerous body parts with the intake of Ascaris lumbricoides present in food and water. These study methods were implemented at the Saidu Teaching Hospital Radiology department from December 2021 to January 2023. This study includes the participants suffering from biliary ascariasis admitted or visited Saidu Teaching hospital in that time frame. Clinical assessment of the participants was done based on the appearance of signs and symptoms present in them. The participant's laboratory test was done to determine the level of basic body parameters, after that ultrasonography was used to diagnose the presence and appearance of worms. Endoscopic retrograde cholangiopancreatography (ERCP) was used to extract worm from biliary channels, and the incidence of post-ERCP biliary ascariasis was accessed with ultrasonography. This study's results show the presence of numerous types of worms in biliary channels of patients. Also, the level of body parameters, for instance, neutrophil, hemoglobin, and others were compared at the time of admission, and at the time of discharge from the hospital. Furthermore, the incidence of post-ERCP biliary ascariasis was reported as 4% in females, and 1% in males respectively.

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Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Untitled

2023

IJRRT

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“…Mirizzi syndrome may also result from an inflammatory process secondary to erosion caused by an embedded gallstone in the gallbladder infundibulum or in Hartmann's pouch and cystic duct [47]. Imaging modalities such as US, computed tomography, ERCP, and magnetic resonance cholangiopancreatography (MRCP) are useful in making the preoperative diagnosis in patients with clinical findings of obstructive jaundice [48]. Symptoms are similar to those of cholecystitis but can be confused with other obstructive conditions such as cholangitis caused by the presence of choledochal stones and jaundice.…”

Section: Mirizzi Syndromementioning

confidence: 99%

Clinical Conditions, Complications of Cholelithiasis, and Symptom Scoring Suggestion

Aydin

2024

Gallstone Disease - Newer Insights and Current Trends

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Gallstones in the gallbladder are asymptomatic in many patients but can cause serious morbid and mortal problems in a significant number of patients. In addition to simple symptoms such as nausea, vomiting, and abdominal pain, gallstones can cause serious complications such as cholecystitis, cholangitis, bile duct obstruction, pancreatitis, biliary perforation, biliary fistula, and biliary neoplasty. It is important that the problems that may arise due to gallstones are adequately known by physicians and even by patients and their relatives. Being unaware of the possible effects of gallstones can lead to under-treatment and serious complications. Assigning a score to the symptoms and clinical conditions associated with gallstones in proportion to their severity and making accurate comparisons with these scores in clinical trials is important for the use of common language and convenience in studies.

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“…The probability for native liver survival (NLS) was increased if KP was performed before 30 to 45 days postpartum (p.p.) depending on source [18][19][20][21][22][23][24][25][26][27][28]. Screening methods, such as the stool color card and blood analysis for conjugated bilirubin are associated with early diagnosis and lower risk of liver transplantation leading to a live-saving and costeffective outcome [29][30][31][32][33][34].…”

Section: Introductionmentioning

confidence: 99%

Biliatresone and Biliary atresia – Disease modelling in C57BL/6J neonates

Schmidt

Hagens

Schuppert

et al. 2023

Preprint

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Exposure to plant toxins or microbiota that are able to digest common food ingredients to toxic structures might be responsible for biliary atresia (BA). An isoflavonoid, biliatresone is known to effectively alter the extrahepatic bile duct (EHBD) development in BALB/c mice. Biliatresone causes a reduction of Glutathione (GSH) levels, SOX17 downregulation and is effectively countered with N-Acetyl-L-cysteine (NAC) treatment in vitro. Therefore, reversing GSH-loss appears to be a promising treatment target for a translational approach. Since BALB/c mice have been described as sensitive in various models, we evaluated the toxic effect of biliatresone in robust C57BL/6J mice and confirmed its toxicity. Comparison between BALB/c and C57BL/6J mice revealed similarity in the toxic model, indicating that the onset of BA induced by biliatresone is independent of the strain specific different immune systems. Affected neonates exhibited clinical symptoms of BA, such as jaundice, ascites, clay-colored stools, yellow urine and impaired weight gain. The gallbladders of jaundiced neonates were hydropic and EHBD were twisted and enlarged. Serum and histological analysis proved cholestasis. No anomalies were seen in the liver and EHBD of control animals. With our study we join a chain of evidence confirming the BA-inducing effect of biliatresone.

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Imaging in Pediatric Obstructive Jaundice

Cited by 9 publications

References 33 publications

Untitled

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Clinical Conditions, Complications of Cholelithiasis, and Symptom Scoring Suggestion

Biliatresone and Biliary atresia – Disease modelling in C57BL/6J neonates

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