Imaging for pancreatic ductal adenocarcinoma

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide due to its aggressiveness and the challenge to early diagnosis. Complete surgical resection is the only curative option, but fewer than 20% of patients have potentially resectable disease at the time of the diagnosis. Radiologists can assess whether PDAC is resectable, borderline resectable, locally advanced or metastatic based on current imaging tests. This review will outline the role of imaging in both the diagnosis and staging of PDAC, with the goal of assisting the multidisciplinary team in tailoring the best treatment for patients.

Endogenous Anti-Inflammatory Very-Long-Chain Dicarboxylic Acids: Potential Chemopreventive Lipids

“…Deep organ cancers such as colorectal (CRC), kidney, and pancreatic cancers are devastating malignancies which can only be detected by colonoscopy (CRC) or imaging [1,2,3,4]. Of significance, these cancers are characterized by extensive inflammation, which contributes to the tumor microenvironment and is associated with increased risk of developing cancer [5,6,7,8,9,10,11].…”

Diagnostic and therapeutic recommendations in pancreatic ductal adenocarcinoma. Recommendations of the Working Group of the Polish Pancreatic Club

“…Spiral tomography, preferably with the application of a 64-row or above scanner, with slice thickness up to 3 mm, should be performed [9, 15, 17]. Both a neutral oral contrast agent (e.g.…”

“…The two-phase technique includes the pancreatic parenchymal phase (40 to 50 s after contrast administration) and the portal venous phase (after 65 to 70 s). This pancreatic protocol allows for making an appropriate evaluation of morphological, arterial, venous and extrapancreatic changes, which is crucial to determine the disease progression [17].…”

The clinical application of 18F-FDG PET/CT in pancreatic cancer: a narrative review

“…Imaging examinations play an essential role in tumor detection, staging, and surgical resection assessment and can provide reliable evidence for the diagnosis and treatment of pancreatic cancer ( 9 ). Currently, imaging techniques commonly used for pancreatic cancer include endoscopic ultrasound (EUS), conventional ultrasound, magnetic resonance imaging (MRI), multidetector spiral computed tomography (MDCT), positron emission tomography/computed tomography (PET/CT), and others ( 10 , 11 ).…”