Imaging flow cytometry for modern particle analysis

Abstract

Imaging flow cytometry (IFC) is widely accepted as a generic method for population analysis of even huge particle collections. Combined with tailored optical setups, on-chip sample management and task-specific data analysis, it uses modern imaging modalities for high-throughput applications. In our work, we demonstrate the capabilities of a generic microfluidic chip concept, which can be easily customized for applications in conventional and 3D imaging flow cytometry, particle sorting and Brownian motion analysis of nanoparticles.