Imaging findings of a case of intravascular large B-cell lymphoma with cardiac involvement

Abstract

Intravascular large B-cell lymphoma (IVLBCL) is a very rare subtype of malignant lymphoma that is difficult to diagnose. Cases of myocardial infarction caused by IVLBCL are even rarer. Herein, we report a case presenting with heart failure and delayed enhancement in the hypokinetic cardiac septum on contrast-enhanced cardiac magnetic resonance imaging. Myocardial biopsy showed large B-cell lymphoma cells in the microvessels within the myocardium. To the best of our knowledge, this is the first report of imaging findings of cardiac involvement in IVLBCL.

Acute Saddle Embolus With Thrombus in Transit: A Case Report and Review of the Literature

“…While vascular obstruction due to IVLBCL most commonly occurs in the CNS and the skin, there have been a few reported cases of cardiac involvement. Kadoya et al [ 13 ] and Bauer et al [ 14 ] presented evidence of large B-cell lymphoma cell infiltration into the myocardial microvessels at autopsy after death from myocardial infarction. A case of rapidly progressive RV heart failure due to lymphomatous obstruction of pulmonary vessels from IVLBCL has been reported as well [ 15 ].…”