Imaging features of non-epithelial tumours of the larynx

Ng, Chaan S.; Mentias, Youssef; Abdelgalil, Alaa

doi:10.1016/j.crad.2020.01.013

Cited by 4 publications

(1 citation statement)

References 47 publications

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“…4) To facilitate preoperative diagnosis of LA by excluding of malignancy, several studies have evaluated the characteristics of LA on cross-sectional images. [5][6][7] On CT, LA reportedly ap-pears as a well-defined, homogenous, and low-attenuating mass with occasional punctuated calcifications. 6) MRI is regarded as an ideal modality, which demonstrates the characteristic intermediate signal on T1 comparable with that of skeletal muscle, enhancement with contrast, and a low T2 signal reflecting the low water content.…”

Section: Introductionmentioning

confidence: 99%

A Case of Laryngeal Amyloidosis: Role of US and US-CNB for Preoperative Diagnosis

Ahn¹,

Oh²,

Kwak³

et al. 2022

Korean J Otorhinolaryngol-Head Neck Surg

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Amyloidosis is a rare benign disease characterized by the extracellular deposition of nonsoluble fibrillar proteins (amyloids) within organs. Laryngeal amyloidosis (LA) accounts for only 9%-15% of all cases of amyloidosis. Since clinical manifestations and laryngoscopic findings often overlap with those of laryngeal cancer, it is challenging to differentiate LA from laryngeal cancer prior to surgical biopsy. We report a case of LA mimicking laryngeal cancer, in which the diagnosis was facilitated by preoperative ultrasonography (US) and US-guided core-needle biopsy (US-CNB) prior to surgical biopsy. The US findings of this case were distinguishable from those of laryngeal cancer, which enabled us to consider a diagnosis other than laryngeal cancer. Amyloidosis was diagnosed preoperatively using office-based percutaneous US-CNB, avoiding general anesthesia needed for suspension laryngoscopic examination. This case suggests that US and US-CNB could be used as supplementary diagnostic modalities to evaluate suspicious laryngeal masses mimicking laryngeal cancer.

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