Imaging diagnosis of young women with breast cancer

Sentís, Melcior

doi:10.1007/s10549-010-1048-z

Cited by 8 publications

(7 citation statements)

References 24 publications

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“…Although the use of breast implants has no correlation with the risk for BC, their presence lowers the effectiveness of mammogram testing, thus contributing to delayed diagnosis [10,11]. Therefore, women who consider breast implants ought to be informed about that risk.…”

Section: Diagnostic Testingmentioning

confidence: 99%

Breast cancer in young women

Radecka¹,

Litwiniuk²

2016

Ginekol Pol

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Breast cancer (BC) in young women is rare, affecting only 4-6% of women under the age of 40. Regardless, BC remains the most common malignancy among younger patients. Recently, a significant increase in BC rates has been observed among pre-menopausal subjects. Breast cancer in young women requires special attention due to its specific morphologic and prognostic characteristics and unique aspects, including fertility preservation and psychosocial issues (e.g. its impact on family life and career). Young women are more likely to have tumors with higher incidence of negative clinicopathologic features (higher histological grade, more lymph node positivity, lower estrogen receptor (ER) positivity, higher rates of Her2/neu overexpression). Also, they tend to be diagnosed at more advanced stages of the disease. That, in turn, contributes to less favorable prognosis as compared to older women. Young women are generally treated similarly to older patients. Surgical management includes mastectomy or breast-conserving surgery, followed by radiation therapy (younger women have higher local recurrence rates than older women, especially after breast-conserving therapy). Although the basics of chemotherapy are the same for patients of all ages, younger women have some special considerations. It is important to consider options for fertility preservation before starting systemic treatment. Patients should have access to genetic testing as their results may affect the choice of therapy. Younger women and their families should receive adequate psychological support and counselling.

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Section: Diagnostic Testingmentioning

confidence: 99%

Breast cancer in young women

Radecka¹,

Litwiniuk²

2016

Ginekol Pol

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“…2 Breast magnetic resonance imaging (MRI) is currently used for screening women with high-risk of breast cancer, 3 evaluating new breast cancer diagnosis, and other indications such as response to neoadjuvant chemotherapy. 4 Clinical breast MRI protocols include contrast enhanced (CE)-MRI, in which intravenous contrast agents are administered to visualize vascular patterns, such as tumor angiogenesis. The use of contrast agents is contraindicated in pregnant women.…”

Section: Introductionmentioning

confidence: 99%

Correction of Artifacts Induced by B₀ Inhomogeneities in Breast MRI using Reduced Field-of-View Echo-Planar Imaging and Enhanced Reverse Polarity Gradient Method

Rodríguez‐Soto¹,

Park²,

Holland³

et al. 2020

Preprint

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Purpose: Diffusion weighted (DW) echo-planar imaging (EPI) is prone to geometric and intensity distortions due to B0 inhomogeneities. Pulse sequences that excite spins within a reduced field-of-view (FOV) in the phase encoding (PE) direction have been developed to decrease such distortions. In addition, use of the reverse polarity gradient (RPG) method, a retrospective approach to correct distortion artifacts, has been shown to improve the localization of tumor lesions. The purpose of this work was to evaluate the performance of reduced-FOV acquisition and RPG in decreasing distortion artifacts for breast imaging. Methods: EPI data were acquired with full and reduced-FOV in a breast phantom and in a group of 170 women at 3T. The performance of RPG in correcting distortion artifacts in EPI data was evaluated using the mutual information (MI) metric between EPI and anatomical low-distortion images before and after distortion correction. Results: RPG corrected distortions by 61% in full-FOV EPI and 48% in reduced-FOV EPI in a breast phantom. In patients, MI increased on average 13+/-8% and 8+/-6% for both full and reduced-FOV EPI data after distortion correction, respectively. The 95th percentile and maximum displacement between uncorrected and corrected full-FOV EPI datasets were 0.8+/-0.3cm and 1.9+/-0.3cm, and for reduced-FOV were 0.4+/-0.2cm and 1.3+/-0.3cm. Conclusion: Minimal distortion was achieved with RPG applied to reduced-FOV EPI data. RPG improved distortions for full-FOV, but with more modest improvements and limited correction near the nipple.

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“…It is estimated that one in eight U.S. women will develop a form of breast cancer in their lifetime, emphasizing the importance of effective and accurate screening practices 2 . Breast magnetic resonance imaging (MRI) is currently used for screening women with high‐risk breast cancer 3 , evaluating new breast cancer diagnosis, 4 and other indications such as response to neoadjuvant chemotherapy 5 . Clinical breast MRI protocols include contrast‐enhanced (CE)‐MRI in which intravenous contrast agents are administered to visualize vascular patterns, such as tumor angiogenesis 6 .…”

mentioning

confidence: 99%

Correction of Artifacts Induced by B₀ Inhomogeneities in Breast MRI Using Reduced‐Field‐of‐View Echo‐Planar Imaging and Enhanced Reversed Polarity Gradient Method

Rodríguez‐Soto

Fang

Holland

et al. 2021

Magnetic Resonance Imaging

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Background Diffusion‐weighted (DW) echo‐planar imaging (EPI) is prone to geometric distortions due to B0 inhomogeneities. Both prospective and retrospective approaches have been developed to decrease and correct such distortions. Purpose The purpose of this work was to evaluate the performance of reduced‐field‐of‐view (FOV) acquisition and retrospective distortion correction methods in decreasing distortion artifacts for breast imaging. Coverage of the axilla in reduced‐FOV DW magnetic resonance imaging (MRI) and residual distortion were also assessed. Study Type Retrospective. Population/Phantom Breast phantom and 169 women (52.4 ± 13.4 years old) undergoing clinical breast MRI. Field Strength/Sequence A 3.0 T/ full‐ and reduced‐FOV DW gradient‐echo EPI sequence. Assessment Performance of reversed polarity gradient (RPG) and FSL topup in correcting breast full‐ and reduced‐FOV EPI data was evaluated using the mutual information (MI) metric between EPI and anatomical images. Two independent breast radiologists determined if coverage on both EPI data sets was adequate to evaluate axillary nodes and identified residual nipple distortion artifacts. Statistical Tests Two‐way repeated‐measures analyses of variance and post hoc tests were used to identify differences between EPI modality and distortion correction method. Generalized linear mixed effects models were used to evaluate differences in axillary coverage and residual nipple distortion. Results In a breast phantom, residual distortions were 0.16 ± 0.07 cm and 0.22 ± 0.13 cm in reduced‐ and full‐FOV EPI with both methods, respectively. In patients, MI significantly increased after distortion correction of full‐FOV (11 ± 5% and 18 ± 9%, RPG and topup) and reduced‐FOV (8 ± 4% both) EPI data. Axillary nodes were observed in 99% and 69% of the cases in full‐ and reduced‐FOV EPI images. Residual distortion was observed in 93% and 0% of the cases in full‐ and reduced‐FOV images. Data Conclusion Minimal distortion was achieved with RPG applied to reduced‐FOV EPI data. RPG improved distortions for full‐FOV images but with more modest improvements and limited correction near the nipple. Evidence Level 3 Technical Efficacy Stage 1

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Imaging diagnosis of young women with breast cancer

Cited by 8 publications

References 24 publications

Breast cancer in young women

Breast cancer in young women

Correction of Artifacts Induced by B₀ Inhomogeneities in Breast MRI using Reduced Field-of-View Echo-Planar Imaging and Enhanced Reverse Polarity Gradient Method

Correction of Artifacts Induced by B₀ Inhomogeneities in Breast MRI Using Reduced‐Field‐of‐View Echo‐Planar Imaging and Enhanced Reversed Polarity Gradient Method

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Imaging diagnosis of young women with breast cancer

Cited by 8 publications

References 24 publications

Breast cancer in young women

Breast cancer in young women

Correction of Artifacts Induced by B0 Inhomogeneities in Breast MRI using Reduced Field-of-View Echo-Planar Imaging and Enhanced Reverse Polarity Gradient Method

Correction of Artifacts Induced by B0 Inhomogeneities in Breast MRI Using Reduced‐Field‐of‐View Echo‐Planar Imaging and Enhanced Reversed Polarity Gradient Method

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Correction of Artifacts Induced by B₀ Inhomogeneities in Breast MRI using Reduced Field-of-View Echo-Planar Imaging and Enhanced Reverse Polarity Gradient Method

Correction of Artifacts Induced by B₀ Inhomogeneities in Breast MRI Using Reduced‐Field‐of‐View Echo‐Planar Imaging and Enhanced Reversed Polarity Gradient Method