Imaging Diagnosis—metastatic Hemangiosarcoma Causing Cerebral Hemorrhage in a Dog

Dennler, Matthias; Lange, Eva-Maria; Schmied, Oliver; Kaser‐Hotz, Barbara

doi:10.1111/j.1740-8261.2007.00220.x

Cited by 21 publications

(22 citation statements)

References 12 publications

(34 reference statements)

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“…MRI is more sensitive than CT for detecting oedema and lacunar infarction, and can detect changes within 1 h of onset. 12,13 In previous reports, dogs with CVA tended to be geriatric, 4,8,10,14,15 and small and spaniel breeds are predisposed to cerebellar infarction. 8,10 Cerebellar infarction is usually ischaemic in nature 4,10 and often involves the territory of the rostral cerebellar artery.…”

mentioning

confidence: 91%

Computed tomography diagnosis of eight dogs with brain infarction

2010

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confidence: 91%

Computed tomography diagnosis of eight dogs with brain infarction

2010

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“…Grossly and histologically, the nodules analyzed here have the same features aspreviously reported elsewhere (Tucker et al, 2000;Gabor et al, 2006;Hidaka et al, 2006;Dennler et al, 2007). When HSA is suspected, immunohistochemistry for von Willebrand's factor (factor VIII-related antigen) or CD31 can be used to demonstrate endothelial derivation and support the diagnosis.…”

Section: Discussionmentioning

confidence: 65%

Clinical and pathological aspects of multicentric hemangiosarcoma in a Pinscher dog

Martins¹,

Torres²,

Rodríguez³

et al. 2013

Arq. Bras. Med. Vet. Zootec.

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“…T1W iso-to hyperintense and T2W hypointense signal, which is accentuated to signal voids in T2*W are consistent with early subacute hemorrhage (Thomas et al 1997). This is an unspecific finding and was described with metastatic hemangiosarcoma (Dennler et al 2007), hemangioma (Eichelberger et al 2011) and intratumoral hemorrhage in choroid plexus tumors in dogs (Wisner et al 2011). With a mixed signal intensity in T1W and T2W and a signal void (T2*) hemangiosarcomas appear in dogs.…”

Section: Discussionmentioning

confidence: 97%

Magnetic resonance imaging of an equine ependymoma

Leser¹,

Flatz²,

Brühschwein³

et al. 2013

PHK

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SummaryA 16-year-old Warmblood gelding was presented with head tilt and a history of increasing numbers of seizures with alterations in consciousness. After each seizure the horse was depressed and quiet whereas before the episodes the gelding was restless, distracted and showed signs of discomfort (chewing, rolling its eyes). In the interictal period the horse was normal. Magnetic resonance imaging revealed a third ventricle mass and ventriculomegaly of the third and lateral ventricles. Histology of the mass was consistent with a well differentiated ependymoma. Keywords Signalment, History, Clinical findingsA 16-year-old warmblood gelding was presented with a 1-year history of progressive changes in mentation and recurrent paroxysmal collapse since 4 weeks. On clinical examination vital parameters were within physiological range (heart rate 40/min, respiratory rate 16/min). Superficial abrasions were evident on the horses` hind limbs. On neurological examination, the gelding was depressed. The horse showed a normal gait while it revealed slight proprioceptive deficits and delayed limb placement correction. Cutaneus trunci reflex and slap test were normal. The horse displayed a mild head tilt to the left with absence of pathological nystagmus. Evaluation of the cranial nerves bilaterally revealed mid-sized nonresponsive pupils. Hence, pupillary light reflex could not be elicited while vision was not impaired. Tongue tone and cervical reflexes were physiological. Examination of tail carriage, anal tone and anal reflex revealed no abnormalities. An intracranial disease was suspected with involvement of the midbrain and reticular activating system. Laboratory examination of blood revealed no abnormal findings. As the owner wanted the diagnostics and treatment to be cost restrictive an attempt was made to rule out infectious or inflammatory conditions by administering drugs. The horse showed no improvement upon treatment with systemic antibiotics, steroids and non-steroidal antiinflammatory drugs. The owner finally elected euthanasia and consented to extended postmortem examinations. ImagingA post-mortem Magnetic Resonance Imaging (MRI) of the neurocranium was performed immediately after euthanasia and cervical transection. All scans were performed with a 1.5 Tesla magnet (Magnetom Symphony, Siemens Medizintechnik, Erlangen, Germany) equipped with a spine coil and CP body array flex coil. The head and cervical spine were placed in left lateral recumbency. Images of the head and brain were acquired with T2-weighted turbo spin-echo (T2W) sequences in sagittal, dorsal and transverse planes (TR 8810 msec; TE 105). A T1-weighted 3D gradient-echo (T1W) sequence with multiplanar reconstruction images in sagittal orientation was acquired (TR 350; TE 17). Scans were accomplished by additional Fluid Attenuated Inversion Recovery (FLAIR; TR 9130; TE 127; TI 2500) and a T2*-weighted gradient echo sequence (T2*W; TR 1000; TE 28) in transverse plane. Dorsal, transverse and sagittal images of the cranial cervical spine (C1-C4) we...

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Imaging Diagnosis—metastatic Hemangiosarcoma Causing Cerebral Hemorrhage in a Dog

Cited by 21 publications

References 12 publications

Computed tomography diagnosis of eight dogs with brain infarction

Computed tomography diagnosis of eight dogs with brain infarction

Clinical and pathological aspects of multicentric hemangiosarcoma in a Pinscher dog

Magnetic resonance imaging of an equine ependymoma

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