Imaging characterization of myocardial function, fibrosis, and perfusion in a nonhuman primate model with heart failure-like features
Xing-Li Liu,
Guan-Zhong Wang,
Mao-Ping Rui
et al.
Abstract:IntroductionThe availability of a human-like chronic heart failure (HF) animal model was critical for affiliating development of novel therapeutic drug treatments. With the close physiology relatedness to humans, the non-human primate (NHP) HF model would be valuable to better understand the pathophysiology and pharmacology of HF. The purpose of this work was to present preliminary cardiac image findings using echocardiography and cardiovascular magnetic resonance (CMR) in a HF-like cynomolgus macaque model.Me… Show more
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