Imaging characteristics of giant myofibroblastoma of the breast diagnosed by ultrasound‐guided core biopsy

Miller, Jeffrey A.; Levine, Charles H.; Simmons, Marc

doi:10.1002/(sici)1097-0096(199709)25:7<395::aid-jcu8>3.3.co;2-d

Cited by 6 publications

(12 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although it most commonly affects elderly men and postmenopausal women [2,11,16,17,19,23], the tumor can occur at any age. Soyer et al [21] reported recently a case of mammary myofibroblastoma in a 10-month old male infant.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Rapidly growing myofibroblastoma of the breast diagnosed in a premenopausal woman: Management and review of the literature

Salemis

Νάκος

Tsiambas

et al. 2013

View full text Add to dashboard Cite

Myofibroblastoma of the breast (MFB) is a rare benign tumor of mesenchymal origin with only 80 cases reported in the literature so far. It most commonly occurs in elderly males and postmenopausal females and grows slowly over a period of months to years. In this study we describe a very rare case of a MFB in a premenopausal woman who presented with a rapidly growing breast mass. Diagnostic evaluation and management of the patient are discussed along with a review of the literature. We conclude that despite its rarity, myofibroblastoma should always be considered in the differential diagnosis of mesenchymal breast tumors. No specific imaging features have been described. Thorough immunohistochemical analysis is crucial to obtain a definitive diagnosis. Local excision is the treatment of choice.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Histologically, the tumor consisted of slender, bipolar spindle cells arranged in fascicular clusters separated by broad bands of hyalinized collagen. MFB is generally a slow-growing tumor with no specific imaging features [6,16,19,25]. We present here a rare case of MFB in a premenopausal female with an unusual clinical presentation.…”

Section: Introductionmentioning

confidence: 99%

Rapidly growing myofibroblastoma of the breast diagnosed in a premenopausal woman: Management and review of the literature

Salemis

Νάκος

Tsiambas

et al. 2013

View full text Add to dashboard Cite

show abstract

“…A mobile, painless mass 8 cm in size was found on physical examination in our case. Rare benign masses of the breast are being detected with the increased use of mammography and ultrasonography in diagnosis of breast cancer (2,3,5). Myofibroblastoma is a heterogeneous round tumor with a well-defined border but without calcification on mammography images.…”

Section: Discussionmentioning

confidence: 99%

“…Finding a cyst in the male patient breast on ultrasonographic investigation is rare. Ultrasonographic evaluation of the male patient breast is a limited imaging method (5). There can be confusion with other masses such as hamartoma, fibroadenoma, or lipoma on imaging (3, 7).…”

Section: Discussionmentioning

confidence: 99%

Myofibroblastoma

Allahverdi¹,

Allahverdi²

2017

J Breasth Health

View full text Add to dashboard Cite

show abstract

“…Association of cartilaginous or smooth muscle areas and giant cells components were also reported (Miller, Levine, & Simmons, 1997). Sometimes, myofibroblastoma may arise in a mammary hamartoma and may present interspersed epithelial structures, which may increase the difficulty of diagnosis (Uchôa et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

Male Breast Cellular Myofibroblastoma With a Rich Reticulinic Network

Gurzu

Jung

2012

Am J Mens Health

View full text Add to dashboard Cite

Myofibroblastoma is a rare mesenchymal tumor located not only in breast but also in extramammary sites. This is the 79th case of breast myofibroblastoma reported in the literature. This tumor presents a great variety of morphological features, which increase the difficulty of differential diagnosis. The authors report a breast myofibroblastoma diagnosed in a 73-year-old male. The article discusses a bilateral gynecomastia and a palpable right breast well-defined tumor, without calcifications on mammography, which was surgically removed. Macroscopically, a well-circumscribed uncapsulated nodule was seen with lobular arrangement on cut section, and microscopically, a nodule with pushing borders and a connective pseudocapsule was seen. The spindle cells were arranged in fascicular clusters, with focally collagen bundles and a rich reticulinic network stained black with Gömöri impregnation. Immunohistochemically, the tumor cells were marked by vimentin, CD34, desmin, and smooth muscle antigen and did not express cytokeratin, S-100 protein, CD99, CD10, and factor VIII–related antigen. More than 90% of the cells expressed estrogen receptor. No recurrences were reported 2 years after surgical excision. This case is a variant of cellular myofibroblastoma, with a rich reticulinic network and scanty collagen bands.

show abstract

Imaging characteristics of giant myofibroblastoma of the breast diagnosed by ultrasound‐guided core biopsy

Cited by 6 publications

References 0 publications

Rapidly growing myofibroblastoma of the breast diagnosed in a premenopausal woman: Management and review of the literature

Rapidly growing myofibroblastoma of the breast diagnosed in a premenopausal woman: Management and review of the literature

Myofibroblastoma

Male Breast Cellular Myofibroblastoma With a Rich Reticulinic Network

Contact Info

Product

Resources

About