Imaging Breast Cancer

Bartella, Lia; Smith, Clare; Dershaw, D. David; Liberman, Laura

doi:10.1016/j.rcl.2006.10.007

Cited by 75 publications

(40 citation statements)

References 110 publications

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“…This type of cancer is slower growing, has a generally good prognosis, is often well defined and, clinically, can feel benign. Invasive ductal carcinoma remains the most common pathological type: 54% in our series compared with the 70-80% general incidence rate [17]. No in situ cancers were detected, which most likely reflects the lack of CT resolution for fine microcalcification, as discussed above.…”

Section: Pathology Of Ct-detected Breast Cancersmentioning

confidence: 46%

“…The pathology of the lesions in our series identified a higher percentage of invasive lobular carcinoma (18%) than the general incidence rate of 5-10% of all breast cancer [17]. Lobular carcinoma can be difficult to diagnose, both clinically and on mammography, because it can spread diffusely through the breast and may present only as subtle distortion.…”

Section: Pathology Of Ct-detected Breast Cancersmentioning

confidence: 56%

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Incidental breast lesions detected on CT: what is their significance?

Moyle¹,

Sonoda²,

Britton³

et al. 2010

BJR

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ABSTRACT. An increasing number of breast lesions are being detected incidentally on CT. The aim of this study was to investigate the rate of referrals to the breast unit for assessment of lesions identified on CT and the resulting yield of previously undiagnosed breast malignancies from this pathway. A retrospective review was undertaken of CT examinations conducted over a period of 14 years. All patients (with no previous history of breast cancer) whose report contained the keyword ''breast'' and who were referred to a specialist breast unit for assessment were reviewed. CT lesion morphology and enhancement pattern were identified and compared with the final diagnostic outcome. 70 patients were identified by retrospective analysis, yielding 78 incidental breast lesions, of which 22 (28.2%) were malignant (category B5). This gave a positive predictive value (PPV) for malignancy of 28.2%. The best morphological predictor of malignancy was spiculation (PPV, 76%) and irregularity (PPV, 58%), whereas calcification patterns (PPV, 36%) were diagnostically unhelpful. Malignant lesions were likely to be larger (mean, 28.5 mm) than benign lesions (mean, 20.2 mm; p,0.05). In conclusion, 30% of incidental breast lesions in this large series of patients proved to be unsuspected breast cancers, particularly irregular spiculated masses. Referral for formal triple assessment of CT-diagnosed breast lesions is worthwhile, and careful examination of the breast should be a routine part of CT examinations.

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Section: Pathology Of Ct-detected Breast Cancersmentioning

confidence: 46%

Section: Pathology Of Ct-detected Breast Cancersmentioning

confidence: 56%

Incidental breast lesions detected on CT: what is their significance?

Moyle¹,

Sonoda²,

Britton³

et al. 2010

BJR

View full text Add to dashboard Cite

show abstract

“…7,8 Thus, even with pressures from healthcare cost containment, the emergence of x-ray tomographic systems [9][10][11] and the relative expense of an exam, the number of breast MR studies is likely to continue to grow in the future because of their exquisite soft-tissue delineation. However, breast MR has a substantial false positive rate-13% to 19% 12,13 -and it is imperfect when used to monitor treatment or follow the breast for recurrence 14,15 due to its reliance on gadolinium as a nonspecific contrast agent. The number of false positives caused by the technique is particularly troubling because of the clinical management burden that is created by the increase in contrast-enhancing foci that need to be evaluated.…”

Section: Introductionmentioning

confidence: 99%

Integration of microwave tomography with magnetic resonance for improved breast imaging

et al. 2013

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Purpose: Breast magnetic resonance imaging is highly sensitive but not very specific for the detection of breast cancer. Opportunities exist to supplement the image acquisition with a more specific modality provided the technical challenges of meeting space limitations inside the bore, restricted breast access, and electromagnetic compatibility requirements can be overcome. Magnetic resonance (MR) and microwave tomography (MT) are complementary and synergistic because the high resolution of MR is used to encode spatial priors on breast geometry and internal parenchymal features that have distinct electrical properties (i.e., fat vs fibroglandular tissue) for microwave tomography. Methods: The authors have overcome integration challenges associated with combining MT with MR to produce a new coregistered, multimodality breast imaging platform-magnetic resonance microwave tomography, including: substantial illumination tank size reduction specific to the confined MR bore diameter, minimization of metal content and composition, reduction of metal artifacts in the MR images, and suppression of unwanted MT multipath signals. Results: MR SNR exceeding 40 dB can be obtained. Proper filtering of MR signals reduces MT data degradation allowing MT SNR of 20 dB to be obtained, which is sufficient for image reconstruction. When MR spatial priors are incorporated into the recovery of MT property estimates, the errors between the recovered versus actual dielectric properties approach 5%. Conclusions: The phantom and human subject exams presented here are the first demonstration of combining MT with MR to improve the accuracy of the reconstructed MT images.

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“…MR imaging is able to detect bulky residual disease at the lumpectomy site and residual disease in the same quadrant [multifocal] or a different quadrant (multicentric). MR imaging can be helpful in the determination of whether the patient would best be served with directed re-excision [residual disease at the lumpectomy site or multifocal disease] or whether the patient warrants a mastectomy (multicentric disease) [26].…”

Section: Suspicion Of Cancer Recurrencementioning

confidence: 99%

Diagnostic Magnetic Resonance Imaging of the Breast

Kılıç

Oğul

Bayraktutan

et al. 2012

EAJM

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Contrast enhanced breast magnetic resonance imaging is a modality that is frequently used into the breast radiologist's daily clinical practice. MRI examination should have optimal technical proficiency in order to attain diagnostic quality avoiding false positive and negative diagnoses. Furthermore, due to increasing usage fields of the examinations uniting with high sensitivity phenomenon, excessive usage and excision/interventional procedures are inevitable. Therefore, we hope to highlight the appropriate usage of the MRI technique and it's clinical applications.

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Imaging Breast Cancer

Cited by 75 publications

References 110 publications

Incidental breast lesions detected on CT: what is their significance?

Incidental breast lesions detected on CT: what is their significance?

Integration of microwave tomography with magnetic resonance for improved breast imaging

Diagnostic Magnetic Resonance Imaging of the Breast

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