Imaging biomarkers for the treatment of esophageal cancer

Hayano, Koichi; Ohira, Gaku; Hirata, Atsushi; Aoyagi, Tomoyoshi; Imanishi, Shunsuke; Tochigi, Toru; Hanaoka, Toshiharu; Shuto, Kiyohiko; Matsubara, Hisahiro

doi:10.3748/wjg.v25.i24.3021

Cited by 17 publications

(12 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In-vivo quantitative information, including texture-analysis, of neoplastic processes of the gastro-intestinal tract may also be derived from images obtained using current state-of the-art CT and MRI imaging [ 59 , 60 ]. Their added clinical value to in-vivo quantitative information derived from FDG/PET images warrants exploration.…”

Section: Discussionmentioning

confidence: 99%

Characterization of FDG PET Images Using Texture Analysis in Tumors of the Gastro-Intestinal Tract: A Review

et al. 2020

View full text Add to dashboard Cite

Radiomics or textural feature extraction obtained from positron emission tomography (PET) images through complex mathematical models of the spatial relationship between multiple image voxels is currently emerging as a new tool for assessing intra-tumoral heterogeneity in medical imaging. In this paper, available literature on texture analysis using FDG PET imaging in patients suffering from tumors of the gastro-intestinal tract is reviewed. While texture analysis of FDG PET images appears clinically promising, due to the lack of technical specifications, a large variability in the implemented methodology used for texture analysis and lack of statistical robustness, at present, no firm conclusions can be drawn regarding the predictive or prognostic value of FDG PET texture analysis derived indices in patients suffering from gastro-enterologic tumors. In order to move forward in this field, a harmonized image acquisition and processing protocol as well as a harmonized protocol for texture analysis of tumor volumes, allowing multi-center studies excluding statistical biases should be considered. Furthermore, the complementary and additional value of CT-imaging, as part of the PET/CT imaging technique, warrants exploration.

show abstract

Section: Discussionmentioning

confidence: 99%

Characterization of FDG PET Images Using Texture Analysis in Tumors of the Gastro-Intestinal Tract: A Review

et al. 2020

View full text Add to dashboard Cite

show abstract

“…However, CT is insensitive for detecting residual disease after neoadjuvant therapy 30 . New techniques, such as dual energy CT 31 , perfusion CT 32 and texture analysis 33 have shown promise in identifying responders to treatment and provide opportunities to personalise neo-adjuvant therapy. (Table 1)…”

Section: Ctmentioning

confidence: 99%

Opportunities in cancer imaging: a review of oesophageal, gastric and colorectal malignancies

Foley

Pearson²,

Riddell³

et al. 2021

Clinical Radiology

View full text Add to dashboard Cite

“…30 Future advances in BE and neoplasia detection may also apply biomarkers to standard imaging techniques, such as CT, MRI, and PET. 31,32…”

Section: Clinical Role Of Advanced Esophageal Endoscopic Imaging For mentioning

confidence: 99%

“…As such, endoscopic mucosal resection has become increasingly a safe first‐line treatment for BE with dysplasia and intramucosal EAC, particularly at BE referral centers, 29 and possibly usurps the role of EUS 30 . Future advances in BE and neoplasia detection may also apply biomarkers to standard imaging techniques, such as CT, MRI, and PET 31,32 …”

Section: Clinical Role Of Advanced Esophageal Endoscopic Imaging For mentioning

confidence: 99%

Advanced endoscopic imaging for detecting and guiding therapy of early neoplasias of the esophagus

Mashimo

Gordon

Singh

2020

Annals of the New York Academy of Sciences

View full text Add to dashboard Cite

Esophageal cancers, largely adenocarcinoma in Western countries and squamous cell cancer in Asia, present a significant burden of disease and remain one of the most lethal of cancers. Key to improving survival is the development and adoption of new imaging modalities to identify early neoplastic lesions, which may be small, multifocal, subsurface, and difficult to detect by standard endoscopy. Such advanced imaging is particularly relevant with the emergence of ablative techniques that often require multiple endoscopic sessions and may be complicated by bleeding, pain, strictures, and recurrences. Assessing the specific location, depth of involvement, and features correlated with neoplastic progression or incomplete treatment may optimize treatments. While not comprehensive of all endoscopic imaging modalities, we review here some of the recent advances in endoscopic luminal imaging, particularly with surface contrast enhancement using virtual chromoendoscopy, highly magnified subsurface imaging with confocal endomicroscopy, optical coherence tomography, elastic scattering spectroscopy, angle-resolved lowcoherence interferometry, and light scattering spectroscopy. While there is no single ideal imaging modality, various multimodal instruments are also being investigated. The future of combining computer-aided assessments, molecular markers, and improved imaging technologies to help localize and ablate early neoplastic lesions shed hope for improved disease outcome.

show abstract

Imaging biomarkers for the treatment of esophageal cancer

Cited by 17 publications

References 57 publications

Characterization of FDG PET Images Using Texture Analysis in Tumors of the Gastro-Intestinal Tract: A Review

Characterization of FDG PET Images Using Texture Analysis in Tumors of the Gastro-Intestinal Tract: A Review

Opportunities in cancer imaging: a review of oesophageal, gastric and colorectal malignancies

Advanced endoscopic imaging for detecting and guiding therapy of early neoplasias of the esophagus

Contact Info

Product

Resources

About