2011
DOI: 10.3174/ajnr.a2782
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Imaging Approaches for Dementia

Abstract: SUMMARY:Brain imaging has progressed from exclusion of rare treatable mass lesions to a specific antemortem diagnosis. MR imagingϪderived hippocampal atrophy and WMH are regarded as imaging biomarkers of AD and CVD respectively. Abnormal FP-CIT SPECT or cardiac iodobenzamide SPECT is a useful supportive imaging feature in the diagnosis of DLB. Frontal and/or anterior temporal atrophy and anterior defects on molecular imaging with FDG-PET or perfusion SPECT are characteristic of FTDs. Whole-body FDG-PET may be … Show more

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Cited by 22 publications
(11 citation statements)
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“…Differing patterns of atrophy can be attributed to the different dementia syndromes: AD = atrophy beginning in the entorhinal cortex and hippocampus, FTD = atrophy in the frontal lobe, and VaD = white matter ischaemia in the frontal white matter and lacunar infarcts [36]. The structural correlation can be used to improve the interpretation of functional imaging [18].…”
Section: Discussionmentioning
confidence: 99%
“…Differing patterns of atrophy can be attributed to the different dementia syndromes: AD = atrophy beginning in the entorhinal cortex and hippocampus, FTD = atrophy in the frontal lobe, and VaD = white matter ischaemia in the frontal white matter and lacunar infarcts [36]. The structural correlation can be used to improve the interpretation of functional imaging [18].…”
Section: Discussionmentioning
confidence: 99%
“…Volümetrik incelemelerde yıllık total beyin atrofisi AH' de %1,4 ila 2,2 iken, normal yaşlanmada (>70 yaş) %0,7'yi aşmaz. Bir çalışmada yıllık hipokampal atrofi AH'li hastalarda %4,7, kontrol grubunda ise %1,4 olarak tespit edilmiştir (42). Atrofi bu hastalığın monitörizasyonunda kullanılır.…”
Section: Kognitif Ve Davranışsal Değerlendirmeunclassified
“…10 2.4 | Alternate to the selection of region of interest (RoI) In some cases, temporal and hippocampal atrophy are exhibited in the brains of cognitively healthy aged people and there is a huge possibility to misclassify them as dementia-affected people.…”
Section: Problems Associated With Automated Dementia Classificationmentioning
confidence: 99%