Imagerie hybride dans l’embolie pulmonaire aiguë : apport de la TDM couplée à la tomoscintigraphie de ventilation et de perfusion

Viau, P.; Franken, Philippe; Padovani, B.; Koulibaly, Pierre Malick; Benoliel, J.J.; Razzouk, M.; Darcourt, Jacques

doi:10.1016/j.mednuc.2010.10.003

Cited by 7 publications

(11 citation statements)

References 15 publications

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“…The results suggest SPECT/CT(Q) may be successfully performed instead of SPECT(V/Q) provided that the data are confirmed in a larger group of patients. Notably, the sensitivity and specificity of SPECT/CT(Q) in the study by Viau et al [4] and in our study were similar.…”

Section: Discussionsupporting

confidence: 87%

“…Viau et al [4] performed SPECT(V/Q) and CT in a group of 75 patients with suspected PE. The EANM guidelines for PE diagnosis were applied.…”

Section: Discussionmentioning

confidence: 99%

“…At our institute, we have performed both perfusion and ventilation SPECT/CT scanning for several years. According to previous publications and our experience, CT may potentially serve as a substitute for ventilation scintigraphy [4,5]. Therefore, the main aim of this study was to evaluate the utility of SPECT/CT(Q) in the diagnosis of PE.…”

Section: Introductionmentioning

confidence: 99%

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The Utility of Hybrid SPECT/CT Lung Perfusion Scintigraphy in Pulmonary Embolism Diagnosis

et al. 2015

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Background: Pulmonary embolism (PE) is diagnosed either by ventilation/perfusion (V/Q) scintigraphy or pulmonary CT angiography. One of the imaging methods used in nuclear medicine is hybrid SPECT/CT scintigraphy. Objectives: The aim of this study was to evaluate the utility of SPECT/CT(Q) scintigraphy in the diagnosis of PE and to compare SPECT/CT(Q) with planar(Q) and SPECT(Q) methods. Methods: The study group consisted of 109 consecutive patients suspected of having PE referred for performing lung scintigraphy. The inclusion criteria were: performance of perfusion planar, SPECT and SPECT/CT scans; availability of clinical data covering a 6-month follow-up period, and D-dimer level testing. The number of eligible patients was 84. PE was reported in patients with at least 1 segmental or 2 subsegmental perfusion defects without parenchymal abnormalities on CT scans. PE was excluded when there was a normal perfusion pattern or perfusion defects were caused by lung parenchymal abnormalities or were not arranged in accordance with the pulmonary vasculature. Results: Twenty-six patients (31%) had a final diagnosis of PE. The sensitivity and specificity values of each method were as follows: planar(Q) 73 and 43%, SPECT(Q) 88 and 47% and SPECT/CT(Q) 100 and 83%. SPECT/CT(Q) yielded a significantly higher diagnostic accuracy than planar(Q) (p < 0.001) and SPECT(Q) (p < 0.001) scans. Conclusions: We conclude that hybrid SPECT/CT(Q) imaging has a high diagnostic efficacy in the diagnosis of PE. Lung perfusion scintigraphy performed with a hybrid SPECT/CT device has a significantly higher sensitivity and specificity than scanning performed with the planar or SPECT technique.

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Section: Discussionsupporting

confidence: 87%

“…Viau et al [4] performed SPECT(V/Q) and CT in a group of 75 patients with suspected PE. The EANM guidelines for PE diagnosis were applied.…”

Section: Discussionmentioning

confidence: 99%

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The Utility of Hybrid SPECT/CT Lung Perfusion Scintigraphy in Pulmonary Embolism Diagnosis

et al. 2015

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“…Dans ce cas, la présence d'anomalies scanographiques à l'évidence non emboliques permet de redresser le diagnostic. Cette aide diagnostique apportée par la TDM à la tomoscintigraphie de perfusion a déjà été démontrée par une équipe du CHU de Nice [23].…”

Section: Discussionunclassified

“…Les tomoscintigraphies de ventilation et de perfusion étaient considérées comme évocatrices d'une embolie pulmonaire dans 25 % des cas pour l'observateur I et dans 19 % des cas pour l'observateur A. Ce taux d'embolie pulmonaire est similaire à d'autres études, comme celle de l'équipe de Nice qui conclue à 21 % d'embolie pulmonaire aiguë dans sa population [23].…”

Section: Caractéristiques De La Population éTudiéeunclassified