Abstract-We present a method to automatically register images based on feature similarity and image decomposing by multiple wavelet-transform. We use GHM multi-wavelet to decompose the image, then use mean-shift image segmentation algorithm to extract the image feature. We serve the regional features as matching primitives, and put forward an improved image registration method based on invariant descriptor. The experimental results show that the algorithm in reducing computational complexity and enhance the algorithm's robustness can get better effect.