“…The pulse coupled neural network (PCNN) was originally developed by Eckhorn in 1990 based on the experimental observations of synchronous pulse bursts in cat and monkey visual cortex [1,2]. As a biologically inspired neural network model, the PCNN possesses numerous unique properties including pulse coupling, pulse synchronization, multiplication modulation and variable threshold [1][2][3], which makes it an efficient alternative in the field of image processing, such as image enhancement [4,5], image segmentation [6,7], image denoising [8,9], object and edge detection [10,11], image fusion [12][13][14][15][16], and so forth. While the PCNN is definitely a parameter-controlled network system [3], the network parameters estimation issue has been considered as a significant factor affecting the overall performance of all the aforementioned PCNN-based image processing applications.…”