This study reports adaptive quantized control for a class of uncertain strict-feedback nonlinear systems with unknown control directions. Combining backstepping technique and Lyapunov stability theory, a systematic analysis method is designed. Based on the disintegration of the hysteresis quantizer, a Nussbaum-based scheme can be developed to get over the obstacle of the quantized input signal and unknown control directions. Moreover, the number of adaptive laws is small, thereby reducing the computational burden. Then we testify the boundedness of all signals in the closed-loop system. Besides, the tracking error can converge to an arbitrarily small domain of origin. Finally, a simulation example is provided to verify the feasibility of the control scheme.