Abstract:Predictive biomarkers of functional or biological age are key for evaluating interventions aimed at increas-ing healthspan and / or lifespan in humans. Currently, cardiovascular performance, blood analytes, frailty indices (e.g. gait speed), and DNA methylation clocks are used to provide such estimates; each technique has its own challenges and limitations. We have developed a novel approach, microscopic imaging of bio-logical age (miBioAge), which computes multiparametric signatures based on the patterns of e… Show more
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