Unplanned readmissions pose a tremendous burden on patients, providers, and payers. Â A significant proportion of readmissions are medication-related. Â Despite the availability of literature regarding hospital-level strategies to reduce readmissions, little has been written about strategies aimed at medication-related readmissions. Â We sought to identify successful readmission reduction strategies by performing a scoping literature review of research published between 2000 and 2017. Â We identified 21 studies that met our inclusion criteria. Â From these studies, we identified 7 components frequently employed as a part of interventions to reduce medication-related readmissions: discharge planning, discharge education, post-discharge telephone calls, the use of a professional coordinator with clinical training to administer the intervention, patient education efforts, provider training efforts, and medication reconciliation. Â Thirty-eight percent of all the interventions identified were associated with a statistically significant reduction in readmissions. Â Of the 7 common intervention components we identified, none were consistently associated with intervention success in the full sample. Â However, interventions implemented by inpatient hospitals, in particular academic medical centers, had a higher success rate than interventions implemented by other providers. Â We examined a subsample of larger studies and found that discharge planning and medication reconciliation components were included in most of the successful interventions. Â Future research should look beyond simply identifying components included in an intervention and should instead seek to identify contextual factors that enable or inhibit the success of these components. Â Research examining discharge planning and medication reconciliation efforts will be particularly important.