“…Ecstasy), methamphetamine (Philopon), and ketamine are included in ATSs. , The use of these stimulants is increasing in popular festivals and raves parties, but they are also being used in cases of drug-facilitated crimes and other occurrences. − Because these stimulants have no color, smell, or taste, people are typically unaware of their presence in drinks, and this situation is aggravated when alcohol consumption is involved. As these drugs can cause physical weakness or loss of consciousness, individuals become unable to protect themselves and are vulnerable to crime. ,, To prevent drug-facilitated crimes, countermeasures are necessary to avoid the unintentional ingestion of drugs. Many technologies, including mass spectrometry, infrared spectrometry, Raman spectroscopy, X-ray diffractometry, thin-layer chromatography (TLC), ultraviolet spectroscopy, immunoassays, urine dipstick tests, and spot/color tests, have been developed for drug testing. − In particular, mass spectrometry-based technologies such as liquid chromatography–mass spectrometry, gas chromatography–mass spectrometry, and matrix-assisted laser desorption/ionization mass spectrometry enable the qualitative and quantitative analysis of drugs with high resolution. − These techniques are commonly applied in forensic drug analysis.…”