Illegal drugs and periodontal conditions

Quaranta, A. Alberigi; D’Isidoro, Orlando; Piattelli, Adriano; Hui, Wang; Perrotti, Vittoria

doi:10.1111/prd.12450

Cited by 9 publications

(5 citation statements)

References 140 publications

(409 reference statements)

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“…CBD can be considered a therapeutic agent for periodontal disease. However, studies have shown the negative effects of cannabis smoking on periodontal health, possibly leading to periodontitis and gingival enlargements 24 . It has been suggested that CBD may promote fibrotic gingival enlargement by increasing the production of fibronectin in gingival fibroblasts 25 .…”

Section: Discussionmentioning

confidence: 99%

“…However, studies have shown the negative effects of cannabis smoking on periodontal health, possibly leading to periodontitis and gingival enlargements. 24 It has been suggested that CBD may promote fibrotic gingival enlargement by increasing the production of fibronectin in gingival fibroblasts. 25 Therefore, the use of CBD in the treatment of periodontitis needs much research.…”

Section: Discussionmentioning

confidence: 99%

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Cannabidiol attenuates periodontal inflammation through inhibiting TLR4/NF‐κB pathway

Chen

Liu

et al. 2023

J of Periodontal Research

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Periodontitis is caused by the dynamic imbalance between microbial virulence factors and host defense. The chronic inflammation of periodontitis leads to the formation of periodontal pockets, progressive loss of soft tissue attachment, and alveolar bone resorption, which can eventually lead to tooth loosening and loss. [1][2][3][4] Hence, anti-inflammatory is of great significance for periodontal treatment.Cannabis, as an ancient medicinal plant, has important agricultural and medicinal values. 5,6 Cannabidiol (CBD) is a non-addictive component in cannabis and has been used to treat epilepsy, cancer, chronic pain, and immune diseases. [7][8][9][10] Moreover, existing research

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cannabidiol attenuates periodontal inflammation through inhibiting TLR4/NF‐κB pathway

Chen

Liu

et al. 2023

J of Periodontal Research

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“…In recent years, the practice of dentistry and periodontology has become complicated by the treatment of an increasing number of patients with substance use disorder. 6 There are many illegal drugs that may have an impact on periodontal health and conditions, including their effect, medical manifestations, risks, and overall impact on oral health and the periodontium. The clinical management of periodontal patients abusing illegal drugs has been reported in a comprehensive approach inclusive of the detection of illicit drug abusers, screening, interviewing and counseling, the referral to treatment, and the dental and periodontal management.…”

Section: Introductionmentioning

confidence: 99%

Risk factors for periodontitis & peri‐implantitis

Darby

2022

Periodontology 2000

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Risk is part of all health professions and generally indicates the chance of getting some form of illness. For dental practitioners this includes periodontitis or peri‐implantitis, the focus of this issue. Many risk factors are involved in the development of disease and most likely interact or overlap. Most patients will probably have multiple risk factors, some of which will be the same for both periodontitis and peri‐implantitis. The most recent classification of periodontal disease recognises the importance of risk factors and contemporary dental practice requires that clinicians be aware of and manage them. Broadly speaking risk factors can be patient, environment or practitioner related. Patient risk factors would include socio‐economic status, smoking, substance use disorders, diabetes, diet and dietary supplements, mental health disorders, old age, poor home dental care or understanding of the need for good home care and use of medications. Environmental modification of the host response through gene function is an emerging risk factor. Lastly, practitioner‐related factors in implant dentistry are now known to affect risk. These would include the use of digital technology, but patient related factors such implant location and the body’s reaction to an implant itself add to the risk of developing disease. This edition of Periodontology provides an uptodate review of many of these risk factors and their impact summarising current knowledge.

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“…The ability to detect a wide range of illicit drugs, such as heroin, cocaine, methamphetamine and mephedrone, is, therefore, a significant challenge whose overcoming will bring great benefits to society. 4,5 The successful detection of such drugs has become a crucial priority to reduce threats and risks to public health, [6][7][8][9][10] which cause serious damage, such as respiratory, cardiac, renal damage and also mental health problems such as violence, depression, anxiety and hallucinations. 11,12 In order to design sensitive, fast, portable, and low-cost sensing nanodevices, it is necessary to develop new nanomaterials and device concepts, and devise new plans and strategies to control, manage, and develop precise sensor chips.…”

Section: Introductionmentioning

confidence: 99%