İlk Tri̇mester Vi̇tami̇n D, Vi̇tami̇n B12 Ve Ferri̇ti̇n Sevi̇yesi̇leri̇ni̇n Preeklampsi̇ İle İli̇şki̇si̇

Gülücü, Selim; Güçlü, Mehmet; Çelik, Sebahattin; CAN, İlkin Seda; Çalışkan, Canan Soyer; Çelik, Samettin

doi:10.46332/aemj.865619

Cited by 2 publications

(1 citation statement)

References 35 publications

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“…Although it is thought to be caused by PE trophoblast invasion disorder and impaired placental blood supply, the pathogenesis is not fully understood. Impaired placental development, increased placental oxidative stress, apoptosis, and necrosis cause endothelial dysfunction, proteinuria, and maternal hypertension 2 .…”

Section: Introductionmentioning

confidence: 99%

Evaluation of first- and third-trimester afamin levels in preeclampsia

Gülücü

Çelik

Unver

2023

Rev. Assoc. Med. Bras.

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OBJECTIVE:The aim of this study was to investigate serum afamin levels in the first and third trimesters in preeclampsia. METHODS: Serum samples from 118 patients in the first and third trimesters were analyzed. Serum samples were collected from pregnant women who had enrolled in the first trimester. Blood was then collected from pregnant women who had developed preeclampsia and from healthy controls in the third trimester. The collected blood samples were resolved for analysis, and serum afamin concentrations were measured in the first and third trimesters. Preeclampsia and healthy controls were compared. RESULTS: There was no significant difference between the control and preeclampsia groups in terms of age, body mass index, and smoking. Afamin levels in the first and third trimesters were higher in the preeclampsia group than in the control group (p<0.05). In the subgroup analysis of the preeclampsia group, afamin levels were higher in the early-onset preeclampsia group than in the late-onset preeclampsia group in the first and third trimesters (p<0.05). In the receiver operating characteristic analysis afamin levels were 96.23 ng/mL in the first trimester and 123.57 ng/mL in the third trimester as cut-off values for preeclampsia. CONCLUSION: Serum afamin levels are useful for predicting preeclampsia in the first trimester in pregnant women and can be used in clinical practice as a supportive biomarker for the diagnosis of preeclampsia in the third trimester. Meta-analyzes are needed to investigate the effect of afamin levels in the prediction and diagnosis of preeclampsia and to determine the cut-off value.

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Section: Introductionmentioning

confidence: 99%

Evaluation of first- and third-trimester afamin levels in preeclampsia

Gülücü

Çelik

Unver

2023

Rev. Assoc. Med. Bras.

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Prevalence of Anaemia in Pregnant Women Registered in a Family Health Centre in Kütahya

Durmaz,

Yılmaz

2024

Sakarya Üniversitesi Holistik Sağlık Dergisi

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Objective: The aim of this study was to determine the prevalence of anaemia in pregnant women enrolled in a family health centre in Kütahya and to determine the proportion of pregnant women with low haemotocrit, low ferritin and vitamin B12 deficiency and some factors affecting them. Method: The population and sample of this retrospective study consisted of 91 pregnant women who were registered to Yıldırım Bayazıt FHC between 01 October and December 2021 and whose medical records were complete. Haemoglobin, haematocrit, ferritin, vitamin B12 values of pregnant women were examined. Results: The mean age of the pregnant women included in the study was 28.83±8.61 years. Anaemia was found in 7 (7.7%), low haemotochrit in 3 (3.3%), low ferritin in 67 (73.6%), and B12 deficiency in 19 (20.9%) of the pregnant women. It was found that haemoglobin, haematocrit and ferritin values of pregnant women did not differ significantly according to age, educational status, number of pregnancies, nutrition and planning status of pregnancy (p>0.05). Conclusion: Low ferritin levels were found to be high in pregnant women in our study group. Ferritin levels of pregnant women should be monitored in Family Health Centres.

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İlk Tri̇mester Vi̇tami̇n D, Vi̇tami̇n B12 Ve Ferri̇ti̇n Sevi̇yesi̇leri̇ni̇n Preeklampsi̇ İle İli̇şki̇si̇

Cited by 2 publications

References 35 publications

Evaluation of first- and third-trimester afamin levels in preeclampsia

Evaluation of first- and third-trimester afamin levels in preeclampsia

Prevalence of Anaemia in Pregnant Women Registered in a Family Health Centre in Kütahya

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