II. Über Versuche der therapeutischen Verwendung von Pineal-Extrakten

Hofstätter, R.

doi:10.1159/000295117

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1938

1976

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“…Several studies indicate that the pineal gland may have an in fluence on tumor growth: Engel [1,2,3,4,5], Bergmann and Engel [6], Hofstatter [7], Sander and Schmid [8], Rodin [9], Barone and Das Gupta [11] postulated that pinealectomy affects both pigmented and non-pigmented tu mors in rats. Lapin [12] studied the influence of pinealectomy and thymectomy on the growth and formation of metastases of the Yoshida sarcoma in rats.…”

Section: Introductionmentioning

confidence: 99%

Effects of Some Low Molecular Weight Sheep Pineal Fractions and Melatonin on Different Tumors in Rats and Mice

Lapin¹,

Ebels²

1976

Oncology

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With these preliminary experiments attention is drawn to a possible relation between tumor development and the pineal. The influence of melatonin and some low molecular weight pineal fractions on the growth and incidence of different experimental tumors was compared. Some pineal fractions which have an effect on the activity of hypothalamus or anterior hypophyses of male rats and mice in vitro may be active in some of these tumor models.

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