Ignatius of Antioch

Schoedel, William R.; Koester, Helmut

doi:10.2307/j.ctvb936zj

Cited by 21 publications

(24 citation statements)

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“…HSC progenitors give rise to definitive HSC which expand, migrate to the fetal liver and colonize the bone marrow around birth, where they persist and function lifelong. In the bone marrow, HSC generate at low rate multipotent progenitors (MPP) (1-5); these progenitors self-renew and play a major role for daily hematopoiesis in the adult (1, [6][7][8]. Transposon-tagging of HSC in situ has indicated the existence of multilineage HSC clones giving rise to lymphoid and myelo-erythroid output, myelo-erythroid-restricted HSC clones lacking lymphoid output, and inactive HSC clones that do not produce differentiated output (6,9).…”

mentioning

confidence: 99%

Resolving fate and transcriptome of hematopoietic stem cell clones

Pei

Shang

Wang

et al. 2020

Preprint

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Adult bone marrow harbors a mosaic of hematopoietic stem cell (HSC) clones of embryonic origin, and recent work suggests that such clones may have coherent lineage fates. To probe under physiological conditions whether HSC clones with different fates are transcriptionally distinct, we developed PolyloxExpress -a Cre recombinase-dependent DNA substrate for in situ barcoding that allows parallel readout of barcodes and transcriptomes in single cells. We describe differentiation-inactive, multilineage and lineage-restricted HSC clones, find that they reside in distinct regions of the transcriptional landscape of hematopoiesis, and identify corresponding gene signatures. All clone types contain proliferating HSCs, indicating that differentiationinactive HSCs can undergo symmetric self-renewal. Our work establishes an approach for studying determinants of stem cell fate in vivo and provides molecular evidence for fate coherence of HSC clones.

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mentioning

confidence: 99%

Resolving fate and transcriptome of hematopoietic stem cell clones

Pei

Shang

Wang

et al. 2020

Preprint

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“…Joly’s arguments were not widely accepted in the years following their initial publication (e.g., Hammond Bammel 1982; Paulsen 1985: 4; Schoedel 1985: 6-7). However, Reinhard Hübner’s 1997 study built upon Joly’s foundation and is continuing to have a significant impact on Ignatian studies, having been reprinted in Hübner (2017: 63-92).…”

Section: Inauthentic Letters and Late Datesmentioning

confidence: 99%

The Date and Authenticity of the Ignatian Letters: An Outline of Recent Discussions

Lookadoo

2020

Currents in Biblical Research

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This article examines recent studies of the date and authenticity of the letters of Ignatius of Antioch. Although the debate has a long history, this article focuses on the most recent period of this debate—from roughly 1997 through 2018. While not wanting to diminish the differences between contributors to this debate, three general views can be adduced. This article begins by highlighting the major players and formative contributors to each view. Of particular note in this most recent phase of debate is the separation of the date of the letters from the question of their authenticity. The article next turns to consider the primary pieces of evidence that are utilized when considering Ignatius’s date: the historical value of the Eusebian evidence, the possibility of interpolations within Polycarp’s Philippians, and Ignatius’s interactions with Second Sophistic rhetoric. The conclusion inquires about whether there is other evidence that might be utilized to aid scholars in dating and evaluating the Ignatian letters more securely.

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“…Thiselton, First Epistle to the Corinthians, 862. 166 See Collins,First Corinthians,416,425. 167 Bailey,Paul through Mediterranean Eyes, Or the lack of adequate data.…”

Section: An Integrative Reading: Paul's Suppermentioning

confidence: 99%

“…Therefore, first and foremost, the insertion of the tradition must be related to what the Lord's Supper is for Paul (11.23a: 'I have received'). 171 As James Dunn puts it, 'Paul cites old tradition as the basis for his understanding of the Supper'. 172 Apparently, as was noted above, Paul's preference is to cite authoritative traditions (cf.…”

Section: An Integrative Reading: Paul's Suppermentioning

confidence: 99%